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This week’s entertainment industry earnings are all about the labor disputes gripping Hollywood, as twin strikes by the

A bear being transported on an Iraqi Airways flight from Baghdad to Dubai Friday caused delays after it escaped from a crate in the cargo hold.

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One morning, Alexander Marlon, a private chef in Greenwich, Connecticut, was given less than two hours to source

Model Bella Hadid recently shared an update on TikTok, that her Lyme disease symptoms had flared up following a tooth infection. The Dutch-Palestinian 26-year-old was diagnosed with Lyme disease in 2012, and in her latest health update, shared she was struggling with its symptoms once again. “There was a low-grade infection underneath the tooth, next to the tooth I thought was suffering (she’s good) which is the one I got a root canal on a year ago. It continued to spread down, causing a low-grade infection in my jaw,” Hadid shared on TikTok. She continued by saying: “Please listen to your bodies my friends! This made my Lyme flare up, which means the Lyme is attacking the places that are suffering i.e. tooth, jaw, gut, brain, spine, bones etc oh, and the entire nervous system.” So, what is Lyme disease? “Lyme disease is an infection caused by a group of bacteria transmitted through an infected tick, giving you a specific set of symptoms,” says Dr Sanjay Mehta, GP at the London General Practice. According to analysis published in the open access journal BMJ Global Health, more than 14% of the world’s population probably has, or has had, tick-borne Lyme disease. But Mehta says you can’t catch it from any tick, only infected ones. The disease can also be seasonal – “It doesn’t die down to zero, but it drops significantly during summer and winter, and peaks during early autumn and spring,” he says. What are the symptoms? Lyme disease can manifest in a variety of different ways – from being asymptomatic, to nerve damage, in more severe cases. “There are two main groups of patients,” says Mehta. “First, there’s the group who catch it early, and they don’t really get any symptoms – they just see they’ve been infected by a tick. “Then there’s the second group of people who don’t get treatment, and although only a very small percentage of them actually end up with symptoms, they are the ones we worry about. “Those patients tend to get three stages of symptoms. First, they might get flu-like symptoms kicking in a week or so after the bite, and a characteristic rash. Second, some might then get symptoms related to their nerves, their heart and their brain, several weeks or months later. “An even smaller number of people might then get the third stage, and these are the symptoms people typically associate with Lyme disease – long-term joint problems and neurological symptoms.” How do you contract Lyme disease? As Lyme disease is passed on exclusively via infected ticks, you can downgrade the disease from unlikely to highly unlikely by avoiding tick-heavy areas or taking precautions within them. “There are areas of the UK known to harbour infected ticks, like the Lake District, the New Forest, the North York Moors, and the Scottish Highlands,” says Mehta. “If you see ticks on your skin, you don’t necessarily get transmission for up to four hours, so if you can remove them, that’s ideal.” If you are going to any of these areas, there are also a few simple things you can do to limit the risk. “Try to keep to paths in grassy, wooded areas, and keep away from long grass and vegetation,” advises Mehta. “It sounds obvious, but shower on your return – often ticks fall off – and check yourself for them too. Wear insect repellent, long T-shirts, and long trousers if possible.” What should you do if you get bitten? The simple answer is, if you’ve gone to a high-risk area and you know you’ve been bitten by something, see a doctor. “It is worth going on to treatment, which is a course of specific antibiotics,” says Mehta. “We do run tests, and the tests are fairly reliable, but the main things are a) have you gone to a risky area? b) have you seen you’ve been bitten? And c) have you developed symptoms?” “The take-home message is to seek medical help if there is a bite, but be aware, it’s only a small percentage of people who end up with problems.” Read More Charity boss speaks out over ‘traumatic’ encounter with royal aide Ukraine war’s heaviest fight rages in east - follow live Study reveals how muscle cells deteriorate with age, hampering injury recovery Tips and tricks to preserve your harvest Is it heat exhaustion or are you just tired?

Fringed by mountains, Turkey's southern Aegean coast is dotted with lively resorts and quaint quays in sleepy villages, pine-backed beaches, and translucent bays studded with ancient ruins.

Beijing concert-goers say they were prevented from displaying rainbow imagery at a pop singer’s performance on Saturday, in

CHARLOTTE, N.C.--(BUSINESS WIRE)--Aug 7, 2023--

Researchers have revealed how muscle cells deteriorate with age, affecting their ability to regenerate and recover after an injury. The findings could help to shed light on why it takes people longer to recover from muscle damage as they age. A team at Nottingham Trent University analysed the genes inside muscle cells, and found the ‘development pathways’ – the different ways in which genes work together to regenerate muscle – become weakened in older cells. We know that healthy muscle regenerates after we’ve had an injury but ageing impairs that regeneration potential and recovery gets harder the older we get Dr Livia Santos, Nottingham Trent University Lead researcher Dr Livia Santos, an expert in musculoskeletal biology in Nottingham Trent University’s School of Science and Technology, said: “This goes some way towards explaining why muscle injuries may take longer to recover as we get older.” She added: “We know that healthy muscle regenerates after we’ve had an injury but ageing impairs that regeneration potential and recovery gets harder the older we get. “What we’ve observed, in terms of what happens inside the cells, helps us to better understand why we don’t heal as well or as quickly in older age. “The pathways that control cell processes and development work differently in older cells and are downregulated, meaning regeneration is impacted the older we get. “If we can understand these pathways, however, we could potentially identify new therapies and interventions to mitigate the problem.” The researchers developed a new approach to examine muscle cells in the laboratory to enable them to observe the different mechanisms that drive muscle ageing. They studied muscle cells from donors, chemically injuring cells after they had been donated and isolated, then assessing how they heal and regenerate back to their pre-injury baseline levels. When they looked at cells from a 20-year-old and a 68-year-old donor, researchers found distinct differences in the development pathways of the younger and older cells. While younger muscle cells fully recovered from the injury, the team found that in older cells the genes expressed less of what they needed to, leaving the cells no longer able to perform in the way they should. According to the researchers, this contributes to reduced regeneration capacity leading to thinner, less robust ‘myotubes’ – a type of cell that can fully develop into a muscle fibre. Muscle regeneration is a complex and finely balanced biological process and is known to deteriorate with ageing, leading to the decline of musculoskeletal health and in some cases metabolic and genetic diseases. Our work enables us to examine muscle cell regeneration across the lifespan and this in turn could be key for future drug discovery for disease related to muscle ageing Researcher Janelle Tarum Janelle Tarum, another researcher on the study, said: “We’ve been able to develop a new approach to assess muscle regeneration which involves a state-of-the-art technique called RNA-sequencing. “There’s a very clear reduced regeneration capacity and weakened recovery of aged cells and we have been able to further understand the factors underlying this impairment. “Our work enables us to examine muscle cell regeneration across the lifespan and this in turn could be key for future drug discovery for disease related to muscle ageing.” The study, which also involved Manchester Metropolitan University and Liverpool John Moores University, is published in the Journal of Tissue Engineering and Regenerative Medicine.

Listen to The Big Take podcast on iHeart, Apple Podcasts, Spotify, Terminal. Three months into the writers’ and

Days of heavy rain have caused severe flooding in China's leading grain-producing region in the northeast, killing 14 people and raising concerns about food security as floodwater inundated farmlands.