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Sometimes hosts offering to rent their vacation home, RV or car through peer-to-peer sharing sites don’t show up at the time they promised to exchange keys

When Michel Sadelain began his decades-long quest to genetically modify immune cells to fight cancer, his peers dismissed his ideas as absurd and even his mother...

The awe-inspiring entries to the Ocean Photographer of the Year 2023 contest have been released.

Plus-size model Ashley Graham took to the runway in a glamorous corset for the Harris Reed show. The show marked the informal start of London Fashion Week – officially running from September 15-19. Graham donned a black gown with a shimmering gold corset and a sweeping shawl, as part of the 10 look show. This isn’t the first time Reed has worked with Graham, 35, having dressed her in a sculptural pale pink and black gown for the 2023 Met Gala. Reed’s catwalks are typically dramatic – previous shows have had performances from actor Florence Pugh and singer Sam Smith – and this season was no different. Entitled ‘Duet’, the collection was inspired by Old Hollywood styles, mixing together masculinity and feminity. Designs on the catwalk used deadstock black velvet and white duchess satin with pops of gold, and played around with exaggerated proportions. One of the standout looks of the show was a black and white evening gown with statement shoulders and a revealing low cut-out at the back – which could have been inspired by the low-slung ‘bumster’ trousers popularised by Alexander McQueen in the Nineties. The largely monochrome nature of the collection was punctuated by metallic accents, with silver and pearl half-moon breast cups on one look, showcasing Reed’s partnership with London-based jewellery brand Missoma. The show was accompanied by vocals from Cosima, a Peckham-born singer-songwriter who wore an off-the-shoulder black and white gown to perform. Watching front row at the Tate Modern in London were activist and model Monroe Bergdorf, Game Of Thrones actress Maisie Williams and Bridgerton’s Charithra Chandran. The show was inspired by Virginia Woolf’s 1928 historical novel Orlando, often seen as one of the earliest representations of trans identity in English language literature. Reed cited the quote: “Different though the sexes are, they intermix. In every human being a vacillation from one sex to the other takes place, and often it is only the clothes that keep the male or female likeness, while underneath the sex is the very opposite of what is above.” Backstage, Reed expressed the need for LGBTQ+ representation. “It’s more important today than ever, because we are seeing so much more hate on the streets. I think it’s getting rapidly more aggressive and more unsafe to be queer and queer presenting in the city,” the Evening Standard reported him as saying. “Casting trans and non-binary individuals in my show potentially runs the risk of turning off some of my Middle Eastern and Asian clients. “As a designer, I walk a very fine balance of not offending too many people to equal sales and build my brand, but I still need to stand behind my messaging.” Reed’s designs are often concerned with gender fluidity and theatricality, both at his eponymous label and in his role as creative director of French fashion house Nina Ricci. In January 2024 he will publish his first book, called Fluid: A Fashion Revolution. Read More Charity boss speaks out over ‘traumatic’ encounter with royal aide Ukraine war’s heaviest fight rages in east - follow live Football legend Michael Owen: My four kids all have opinions about my fashion choices How homeowners are creating pet-specific stylish spaces Sex Education season 4: How vintage finds help characters get their unique style

Sebastian Vettel refused to rule out a return to F1 when questioned about the likelihood of a dramatic comeback. The four-time world champion retired at the end of the 2022 season after two years of frustration at Aston Martin. The finale to his stay in the sport was a far-cry from the glory years, namely with Red Bull with four straight titles from 2010-2013, as well as championship tilts with Ferrari. But Vettel, 36, admits he “can’t exclude” the prospect of a return in the future, when asked by Sky F1’s Martin Brundle whether he would return to the grid in a similar manner to the likes of Fernando Alonso and Kimi Raikkonen. "I can’t say no, because that you don’t know," the German said. "I think it’s something that if you asked all of them, probably some of them would have said ‘no’. And some of them I don’t know, but in the end all of them came back, so I can’t exclude it. "It probably will depend much on when, and obviously it’s not endless, because 36 is not like, ‘yeah in 10 years’ time’. "Maybe I think about it then time has passed but it will depend on the challenge, whatever, but it’s not in my head right now.” A 53-time race winner, Vettel made his F1 debut in 2007 before claiming his first victory at Monza with Toro Rosso in 2008. Yet his last three seasons in the sport – one with Ferrari, two with Aston Martin – saw him finish 13th, 12th and 12th again in the Driver Standings, though did see him take on roles as a climate activist and LGBTQ+ rights campaigner. "I’m enjoying the sort of outlook of the challenge of what to do next,” Vettel added. “It will be the way I see it, the biggest challenge for any racing driver and the biggest challenge for any sportsman, sportswoman, what do you do after? "Because naturally you will be like 30-35, 40-45 - depending on your sport and discipline. And then what? "There’s a lot of life left and life can be great even though you’re not racing, you know, the absolute limit in the fastest car in the world, but you can still do lots of great things that give you great pleasure." Vettel was speaking to Sky ahead of this weekend’s Singapore Grand Prix, where the German won his final race of his F1 career in 2019. Read More Farewell Sebastian Vettel, a four-time F1 champion who stood for something bigger than racing How does Max Verstappen’s win-streak compare to fellow record-holder Sebastian Vettel’s? Alfa Romeo confirm driver line-up for 2024 F1 season F1 Singapore Grand Prix: When is practice on Friday at Marina Bay? Red Bull chief apologises to Sergio Perez over ‘offensive remark’

Tyra Banks is modelling again, this time for Karen Millen.

Alana Hadid walked for Elene Velez at New York Fashion Week.

Luxury-goods companies face the risk of disappointing sales growth in China that will weigh further on their stock

Kris Jenner has filed to trademark her name for use on items including loungewear and jackets.

Buffy fans, there's a new story on the way for you with original cast members

Just months before the death of Spanish dictator Francisco Franco in 1975, Julio Pacheco Yepes says he was arrested and tortured by police for belonging to a left-wing...

A study has shown that millions of women and girls experience debilitating periods, that even cause mental health problems. A survey of 3,000 women and girls in the UK aged 16 to 40 for the Wellbeing of Women charity found that 86 per cent had had mental health problems, such as depression, anxiety and mood changes, in relation to their period, Meanwhile, of those surveyed, 96 per cent had experienced period pain, with 59 per cent saying their pain was severe. 91 per cent had experienced heavy periods, with 49 per cent saying their bleeding was severe. Even though these are common symptoms in women and girls with gynaecological conditions such as endometriosis, adenomyosis, fibroids and polycystic ovary syndrome, the report found that 51 per cent of respondents felt their healthcare professional had failed to take their problems seriously, and 82 per cent said they needed better access to accurate information on period problems. A further one-third never seek medical help, and more than half say their symptoms are not taken seriously, despite other symptoms including pain, heavy bleeding and irregular cycles. Prof Dame Lesley Regan, the chair of Wellbeing of Women, said: “It’s simply unacceptable that anyone is expected to suffer with period symptoms that disrupt their lives, including taking time off school, work, or their caring responsibilities, all of which may result in avoidable mental health problems. “Periods should not affect women’s lives in this way. If they do, it can be a sign of a gynaecological condition that requires attention and ongoing support – not dismissal.” Wellbeing of Women has launched its “Just a Period” campaign, which Regan said aims to address “the many years of medical bias, neglect and stigma in women’s health”. This includes tips on how to get the most out of seeing your GP and what women should do if they feel they have been dismissed by health professionals. Responding to the findings, Dr Ranee Thakar, the president of the Royal College of Obstetricians and Gynaecologists, said: “All too often women are living with debilitating symptoms, waiting to receive support or treatment for far longer than they should. “Access to high-quality information and support about periods, gynaecological conditions and their symptoms is vital to ensuring that women and girls get the help that they need at the right time.” Caroline Nokes, the Conservative MP and chair of the women and equalities committee, which is conducting an inquiry into reproductive and gynaecological health, said: “There is a terrible phrase: ‘Well, it’s just a period, why are you making a fuss about that? Can’t you just get on with it?’ Yet many women and girls are experiencing horrendous period symptoms and gynaecological conditions. Endometriosis alone affects 1.5 million women in the UK and costs the economy £8.2bn. Now is the time for change.” Anneliese Dodds, the shadow secretary of state for women and equalities, said: “Over the past few years, we have opened up the conversation around the menopause, and now we need to see this change with periods as well.” Sign up to our free Indy100 weekly newsletter Have your say in our news democracy. Click the upvote icon at the top of the page to help raise this article through the indy100 rankings.