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Beijing concert-goers say they were prevented from displaying rainbow imagery at a pop singer’s performance on Saturday, in

Researchers have revealed how muscle cells deteriorate with age, affecting their ability to regenerate and recover after an injury. The findings could help to shed light on why it takes people longer to recover from muscle damage as they age. A team at Nottingham Trent University analysed the genes inside muscle cells, and found the ‘development pathways’ – the different ways in which genes work together to regenerate muscle – become weakened in older cells. We know that healthy muscle regenerates after we’ve had an injury but ageing impairs that regeneration potential and recovery gets harder the older we get Dr Livia Santos, Nottingham Trent University Lead researcher Dr Livia Santos, an expert in musculoskeletal biology in Nottingham Trent University’s School of Science and Technology, said: “This goes some way towards explaining why muscle injuries may take longer to recover as we get older.” She added: “We know that healthy muscle regenerates after we’ve had an injury but ageing impairs that regeneration potential and recovery gets harder the older we get. “What we’ve observed, in terms of what happens inside the cells, helps us to better understand why we don’t heal as well or as quickly in older age. “The pathways that control cell processes and development work differently in older cells and are downregulated, meaning regeneration is impacted the older we get. “If we can understand these pathways, however, we could potentially identify new therapies and interventions to mitigate the problem.” The researchers developed a new approach to examine muscle cells in the laboratory to enable them to observe the different mechanisms that drive muscle ageing. They studied muscle cells from donors, chemically injuring cells after they had been donated and isolated, then assessing how they heal and regenerate back to their pre-injury baseline levels. When they looked at cells from a 20-year-old and a 68-year-old donor, researchers found distinct differences in the development pathways of the younger and older cells. While younger muscle cells fully recovered from the injury, the team found that in older cells the genes expressed less of what they needed to, leaving the cells no longer able to perform in the way they should. According to the researchers, this contributes to reduced regeneration capacity leading to thinner, less robust ‘myotubes’ – a type of cell that can fully develop into a muscle fibre. Muscle regeneration is a complex and finely balanced biological process and is known to deteriorate with ageing, leading to the decline of musculoskeletal health and in some cases metabolic and genetic diseases. Our work enables us to examine muscle cell regeneration across the lifespan and this in turn could be key for future drug discovery for disease related to muscle ageing Researcher Janelle Tarum Janelle Tarum, another researcher on the study, said: “We’ve been able to develop a new approach to assess muscle regeneration which involves a state-of-the-art technique called RNA-sequencing. “There’s a very clear reduced regeneration capacity and weakened recovery of aged cells and we have been able to further understand the factors underlying this impairment. “Our work enables us to examine muscle cell regeneration across the lifespan and this in turn could be key for future drug discovery for disease related to muscle ageing.” The study, which also involved Manchester Metropolitan University and Liverpool John Moores University, is published in the Journal of Tissue Engineering and Regenerative Medicine.

Days of heavy rain have caused severe flooding in China's leading grain-producing region in the northeast, killing 14 people and raising concerns about food security as floodwater inundated farmlands.

Bella Hadid has shared a candid post reflecting on her health journey as she has lived with Lyme disease since 2012. The 26-year-old supermodel shared a health update with her 59.3 million followers on Instagram on Sunday (6 August) and said she is “finally healthy” after more than a decade of struggling with her health. She shared a number of photographs taken during her treatments over the years, showing her receiving drips and injections, laying in hospital beds as nurses gave her medication, and health documents from her medical record. In her lengthy caption, Hadid wrote: “The little me that suffered would be so proud of grown me for not giving up on myself. Living in this state, worsening with time and work while trying to make myself, my family and the people who support me, proud, has taken a toll on me in ways I can’t really explain.” “To be that sad and sick with the most blessings/privilege opportunity/love around me was quite possibly the most confusing thing ever,” she reflected. She reassured fans that she was “OK and you do not have to worry”, and said that despite her struggles, she “wouldn’t change anything for the world”. “If I had to go through all of this again, to get here, to this exact moment I’m in right now, with all of you, finally healthy, I would do it all again. It made me who I am today,” Hadid continued. The model, who was named one of Time magazine’s 100 most influential people in the world this year, “promised” fans who were also struggling that things “will get better”. “Take a step away, stay strong, have faith in your path, walk your truth and the clouds will start to clear up,” she wrote. “I have so much gratitude for and perspective on life, this 100+ days of Lyme, chronic disease, [co-infection] treatment, almost 15 years of invisible suffering, was all worth it if I’m able to, God-willing, have a lifetime of spreading love from a full cup and being able to truly be myself, for the first time ever.” Hadid explained that she chose photos that were “the most positive” throughout her health journey in an attempt to illustrate how it has been “the most enlightening experience of my life filled with new friends, new visions and a new brain”. She thanked her mother, Yolanda Hadid, who was also diagnosed with Lyme disease in 2012 alongside her son and Hadid’s younger brother Anwar, for “keeping all of my medical records, sticking by me, never leaving my side, supporting, but most of all, believing me through all of this”. Hadid also thanked the brands and companies she has worked with, her agents for “protecting me”, and her medical team, adding: “I love you SO much!!!” She told fans that she would be “back when I’m ready”, adding: “I miss you all so much. I love you all so much.” Lyme disease is a bacterial infection that can be spread to humans by infected ticks and if usually diagnosed based on symptoms, which include fever, headache, fatigue or skin rash, or laboratory testing. Earlier this year, Hadid spoke about some of the symptoms she gets when her Lyme disease flares up. In a TikTok video, she said: “My skin changes colour, I break out randomly, I get (what feels like) lesions, lethargy, chronic anxiety, zero motivation or purpose, leaky gut, adrenals, depression.” She added that she “hates looking in the mirror or taking pictures” of herself because of how the disease impacts her appearance. “If I’m all dolled up, maybe I’ll try for the girls but, man, is it hard to do this as your profession while also feeling/looking sick like this,” she said. Read More Doing things alone isn’t ‘self-love’ – we don’t need to make everything empowering Jamie Foxx and Jennifer Aniston issue statements over ‘antisemitic’ Instagram post Will Smith says daughter Willow’s ‘mutiny’ changed his view on success Is it heat exhaustion or are you just tired? Will Smith says Willow ‘mutiny’ changed his view on family success Health expert Dr Michael Mosley shares two tips for avoiding osteoporosis

Whether you’re away on holiday or lounging in the sun at home, needing a siesta after lunch or a disco nap before dinner on a hot summer’s day is normal. But how can you tell when warm weather-induced drowsiness is something more serious? We asked doctors to explain… What is heat exhaustion? “Prolonged exposure to the heat can cause heat exhaustion. It is the body’s response to excessive loss of water and salt,” says Dr Preethi Daniel, deputy medical director at London Doctors Clinic. “Symptoms may be characterised by heavy sweating, rapid breathing, headache, high temperature, nausea, a faster and weak pulse, light-headedness, feeling fatigued and heat cramps.” Older people, babies, children and those with chronic illnesses are much more likely to develop heat exhaustion. “Symptoms are usually the same in adults and children, and can make children tired and floppy,” says Dr Luke Powles, associate clinical director at Bupa Health Clinics. While not life-threatening, heat exhaustion is a warning sign that you need to cool down promptly to prevent progression to heat stroke, which means getting out of the sun immediately. “Remove any unnecessary clothing, lie down and raise your feet so they are above the level of your heart and drink plenty of water,” says Powles. “You can also use a cool sponge to cool your skin. Make sure someone stays with you until you feel a bit better – which you should do in half an hour or so.” If you don’t start to cool down after 30 minutes, see medical help, as you may have developed heatstroke. What is the difference between heat exhaustion and tiredness? “Heat exhaustion is the direct result of spending too much time in the sun and often raises your core body temperature to over 38 degrees, which isn’t an indicator of general tiredness,” says Dr Carolyn Barshall, GP at independent charitable hospital King Edward VII’s. “Whereas tiredness can be caused by many lifestyle factors such as disordered sleeping patterns, alcohol and poor diet.” Daniel adds: “If you have a lack of energy or aches and pains, consider it tiredness, but if you have any of the other symptoms mentioned above, it could be heat exhaustion.” What is heatstroke? “Heatstroke is the end result of overheating,” says Daniel. “Our internal temperature rises and creates confusion, drowsiness and can lead to seizures.” Much more serious than heat exhaustion, it can cause a change in mental status such as, Barshall says: “Confusion, delirium, combativeness, seizures, loss of consciousness, and a core body temperature above 40 degrees.” Symptoms may also include skin that’s not sweating even when it feels hot, fast breathing or shortness of breath. “Heat exhaustion and heatstroke are often confused, but there is a difference,” says Powles. “Heatstroke should be treated as an emergency, whereas with heat exhaustion, the person needs to be cooled down.” If you suspect someone has heatstroke you should call 999 or seek emergency help immediately. How to stay safe in the sun To prevent heat exhaustion during summer, it’s important not to spend too long in the sun and to stay hydrated. “Avoid direct sunlight between 11am and 3pm, and wear light-coloured, loose clothing,” says Daniel. “Drink plenty of cold drinks and water throughout the day and limit alcohol intake.” To help little ones, she says: “You can keep a pram or buggy cool by covering it with a damp cloth and refreshing it every 30 minutes.” Read More Charity boss speaks out over ‘traumatic’ encounter with royal aide Ukraine war’s heaviest fight rages in east - follow live King Charles enjoys a wee dram at the Met Highland Gamesv Why have the birds disappeared from my garden? Top Films: w/c Saturday, August 12

Health “guru” Dr Michael Mosley has offered his advice to those seeking to reduce their risk of developing osteoporosis, a condition characterised by weak or brittle bones. The medical expert and former doctor is known for his regular appearances on The One Show, as well as his TV programmes on health and medicine. Writing in his column for MailOnline, the creator of the 5:2 and Fast800 diets said he had found his bones were not as strong as they could be while filming a series about healthy ageing in 2022. “Like many Britons, my bones are weaker than they should be,” he wrote. “While filming a series about healthy ageing last year, I had a DXA scan, which uses low-dose X-rays to see how dense (or strong) your bones are. “Although I have a sturdy spine, my hip bones aren’t in great shape, though I don’t have osteoporosis.” Dr Mosley explained that the key to avoiding osteoporis involves getting a healthy intake of both calcium and Vitamin D, as well as a short but effective burst of exercise each day. “As well as obvious good calcium sources such as dairy and leafy green veg, you may want to top up on prunes,” he suggetsed. “A study last October in the American Journal of Clinical Nutrition, involing 235 older women, concluded eating five to six prunes a day improved bone density. The theory is that anti-inflammatory compounds in prunes may slow bone breakdown.” He also suggested that daily exercise could also help, citing a study that showed two minutes of hopping each day can improve hip bone strength. In 2020, Dr Mosley claimed that men were “more deluded” than women when it came to their own weight and fitness, while fronting a Channel 4 series to help people who had gained weight during lockdown. He told the Press Association: “An awful lot of people are unaware of how much weight they put on, particularly around the gut.” Research shows that only 10 per cent of people who are obese know they are but that the figure is only 7 per cent for men, Dr Mosley said, while “women are more aware of it”. He also denied that the show, which offers practical advice to overhaul viewers’ lifestyles, was about fat shaming: “Body shaming is awful. It is incredibly ineffective. Telling people they’re fat never, ever works,” he said. “None of this is about fat-shaming. It is entirely about helping people who are obese and who want to do something about it. Any diet is only ever going to work if the person wants to do it.” Read More Jamie Foxx and Jennifer Aniston issue statements over ‘antisemitic’ Instagram post Why is every celebrity couple breaking up? Relationship experts think we shouldn’t be so shocked Eye masks, kombucha and ‘the full spectrum of milks’: Gwyneth Paltrow finally gave us a tour of her fridge Health expert Dr Michael Mosley shares two tips for avoiding osteoporosis Will Smith says Willow ‘mutiny’ changed his view on family success Who was controversial vegan raw food influencer Zhanna D’Art:

Zhanna Samsonova was just 39 when she died, reportedly from “starvation and exhaustion”, thousands of miles from her birthplace in Moscow, Russia. The Instagram influencer’s tragic story has come under scrutiny due to her promotion of a completely “raw” diet, which reports have suggested was linked to her death. Under the name Zhanna D’Art, Samsonova regularly wrote about how she subsisted exclusively on fruit, vegetables, seeds, smoothies and juices while living in Malaysia. Her mother, Vera, attributed Samsonova’s death to a “cholera-like infection” that was exacerbated by her diet. In recent weeks, Samsonova had been unusually quiet on Instagram, with the exception of a troubling post shared just days before her death on 21 July. “Life is meaningless but worth living provided you recognise it’s meaningly,” she wrote, over a photo of herself wearing sunglasses, with a gasping expression on her face. Vera, 63, told Russian newspaper Novye Izvestia how she had begged her daughter to return home as she feared for her health. “I understood that Zhanna was about to die, but still I could not help her in any way. My daughter's life has turned into a nightmare,” she said, via LBC. She told the publication that she had “fought for years” to save her daughter, once an aspiring model, but she “refused to listen”. Samsonova is believed to have left Russia in 2006, buying a one-way ticket to spend the past 17 years travelling around Asia while blogging and practicing yoga. Photos shared by Vera showed a smiling Samsonova apparently taking part in a modelling contest. The images are in stark contrast to the final photos she shared of herself before her death, where she appeared visibly gaunt and malnourished. Her friends also spoke with local media, confessing they feared she was suffering from anorexia and that her diet was becoming increasingly limited. One of her neighbours, who was not named, said she was “horrified” when they met in Sri Lanka a few months ago, as Samsonova looked “exhausted” and had swollen legs “oozing lymph”. “They sent her home to seek treatment. However, she ran away again. When I saw her in Phuket, I was horrified,” the friend said, according to The Sun. “I lived one floor above her and every day I feared finding her lifeless body in the morning. I convinced her to seek treatment, but she didn’t make it.” Samsonova regularly made claims about the supposed benefits of her raw food diet, including that it offered “natural” protection from Covid-19. She also claimed that her body did not “require” water, writing last year that her fruit-based diet meant she had gone without water for the past six years. In recent months, she appeared to have become a fan of the durian fruit, sharing frequent posts that promoted it. “It’s that fabulous time of year again – Durian Season in Thailand!” she wrote in the caption of one of her final videos. “Wake Up And Smell the Durian! For all you durian lovers out there, isn’t it just the best? And for those who haven’t yet experienced the joy of durian, you’re in for a wild ride!” When she died, Samsonova had around 16,000 followers. At the time of writing, however, that number had increased to 33,000. There have been previous cases where people have starved to death due to their extreme diets, including children whose food intake was controlled by their parents. Last year, a vegan mother was sentenced to life in prison over the death of her 18-month-old son, who was fed a diet of raw fruits and vegetables. Prosecutors said that Sheila O’Leary’s son Ezra was severely malnourished, and weighed just 17 pounds when he died in September 2019. O’Leary was convicted by a Florida jury in June 2022 of first-degree murder, aggravated child abuse, aggravated manslaughter of a child, child abuse and two counts of child neglect. For anyone struggling with the issues raised in this article, eating disorder charity Beat’s helpline is available 365 days a year on 0808 801 0677. NCFED offers information, resources and counselling for those suffering from eating disorders, as well as their support networks. Visit eating-disorders.org.uk or call 0845 838 2040 Read More Vegan raw food influencer ‘dies of starvation and exhaustion’ ‘Love, obsession, extortion and murder’: The dramatic downfall of TikTok influencer who became a killer Royal family silent as Meghan Markle celebrates 42nd birthday Who was controversial vegan raw food influencer Zhanna D’Art: Health expert Dr Michael Mosley shares two tips for avoiding osteoporosis Will Smith says Willow ‘mutiny’ changed his view on family success

Will Smith says a “mutiny” by his daughter, Willow Smith, is what first caused him to change his perspective of success. The Hollywood actor has been stepping back into the spotlight following his infamous outburst at the 2022 Oscars, where he slapped Chris Rock on stage after the comedian made a joke about his wife, Jada Pinkett Smith. In an interview with fellow actor and comedian Kevin Hart, on his Peacock show Hart to Hart, Smith spoke about the moment his family rose to fame in 2010. While Smith had enjoyed his own success from 1999 thanks to NBC’s sitcom The Fresh Prince of Bel Air, Willow and his son Jada achieved their own fame in the early Noughties. Musician Willow, 22, released her debut single “Whip My Hair” in 2010, breaking into the UK and US charts when she was just nine years old. Meanwhile Jaden, a rapper and actor, starred opposite Jackie Chan and Taraji P Henson in The Karate Kid that same year, when he was 11. “2010 was like the greatest year as an artist, as a parent,” Smith told Hart, Metro reports. “Karate Kid came out in June and ‘Whip My Hair’ came out in October. I’m building this dream of a family I’ve had in my mind. I’m going to do it better than my father did it. We’ve talked about it, my father was abusive.” Smith seemed to imply that he was too hard on his family while trying to achieve the vision he had of a successful family. “‘No one wanted to be in a platoon,” he said. “Willow was the first one to begin the mutiny and it was my first realisation that success and money don’t mean happiness. “Up until that point, I really believed that you could succeed your way – to a house and a family – and you could win your way to happiness.” In a 2022 interview with The Independent, Willow Smith revealed that her parents struggled to understand her while she was growing up, due to their different upbringings. Meanwhile Jaden, 25, asked to become emancipated – where a child is removed from the control of their parents or legal guardians – from his parents when he was a minor, aged 15. His request came after he starred opposite his father in the box-office disaster, After Earth, which was also panned by critics. In his 2021 memoir, Smith recalled the moment his “heart shattered” when Jaden asked to become emancipated. “And what was worse was that Jaden took the hit,” the Independence Day star wrote, adding: “Jaden had faithfully done everything that I’d instructed him to do, and I had coached him into the worst public mauling he’d ever experienced.” Jaden ultimately decided against pursuing emancipation, but moved out of his family home that year. Will Smith is currently shooting a Bad Boys sequel with Martin Lawrence, with whom he has co-starred in three previous Bad Boys films, including the 1999 original. Read More Netflix leaves fans distraught as it announces end of beloved series One Tree Hill star Sophia Bush changes name after ‘filing for divorce’ from husband Grant Hughes Zhanna D’Art: Who was the controversial vegan raw food influencer who died from ‘starvation’? Who was controversial vegan raw food influencer Zhanna D’Art: Eva Mendes reveals she doesn’t let her daughters use the internet What is Stiff Person Syndrome?

Eva Mendes has revealed that she doesn’t let her and Ryan Gosling’s daughters use the internet. The actor, 49, took to Instagram on 3 August to share one of the rules that she has for her and Gosling’s daughters - Esmeralda, eight, and Amada, seven. Mendes shared a video of herself shaking her head no and wagging her finger, as she pointed out that’s how she responds to her children when they ask to use the internet. “When my kids ask me if they’re old enough to go on the internet, social media or anything requiring wifi,” she wrote in the caption. When a fan in the comments asked when she will allow her children use the internet, Mendes candidly confessed that she’s still figuring that out. She also specified that she’s been doing research on how social media can impact children as they continue to get older. “I honestly don’t know. I have to see where it goes,” the Hitch star responded. “For now, I’m observing them and keeping up with research about how social media can impact a child’s brain.” She responded to another fan who praised her parenting decision, with Mendes noting that while she’s “just sharing what [she] feels now”, she thinks it’ll be harder to keep her children away from the internet as they get older. Mendes clarified that her children are still given screentime, adding: “I let my kids use the iPad to make movies and watch films I’ve downloaded, but I don’t have internet access on the iPad.” The actress was also hit with some criticism for her parenting rule, with one Instagram user writing: “We are in the internet century so eventually everyone will need or want to access the internet sorry.” While it appears the comment has since been deleted, Mendes responded to the remark by explaining why she doesn’t feel like the internet is a safe space for her children. “In my house, children do not have access to the internet,” she responded to the remark, as reported by E! News. “It’s too dangerous. Just like drinking or voting or getting a driver’s license (etc..) isn’t allowed for children, the internet falls under that category for me. Especially social media.” While Mendes and Gosling - who’ve been together since 2011 - are notoriously private about their family life, the couple have shared a few details about raising children together. During an interview with Byrdie in July 2022, Mendes explained that she and her partner want to make sure that their children feel confident in themselves throughout everything they do in life. “Hopefully Ryan and I are doing the work by just loving them, completely loving them, and doing most of that work for them so that they grow up feeling like they’re enough,” she said. “That’s the one thing that’s really important to me. Because once they feel like they’re enough, no matter what they do, no matter what they end up doing, that will feed into every area of your life. Especially into how attractive you feel, or any of that stuff.” In a cover story interview with GQ in June, Gosling also shared some candid thoughts about fatherhood. He revealed that prior to his relationship with Mendes, he didn’t think much about becoming a father. However, that all changed when Mendes told him she was pregnant. “Eva said she was pregnant,” he recalled. “I would never want to go back, you know? I’m glad I didn’t have control over my destiny in that way, because it was so much better than I ever had dreamed for myself.” Elsewhere in the interview, the Barbie star clarified previous comments he made about the moment Mendes learned she was pregnant. While he maintained that he “wasn’t thinking about kids” before they met, Gosling said: “After I met Eva, I realised that I just didn’t want to have kids without her.” Read More Eva Mendes shows off dress made out of sponges as she jokes it’ll be her Oscars outfit Ryan Gosling’s daughters hilariously prove ‘nobody plays with Ken’ Ryan Gosling’s subtle tribute to Eva Mendes at the Barbie premiere Eva Mendes reveals she doesn’t let her daughters use the internet What is Stiff Person Syndrome? Nearly half of US adults are interested in taking weight loss prescription drugs

The US Food and Drug Administration approved Astellas Pharma Inc.’s Izervay for the treatment of age-related macular degeneration,

A new survey has found that nearly half of adults in the United States are interested in taking prescription drugs for weight loss, such as Ozempic or Wegovy. In a KFF health tracking poll published on 3 August, researchers reported that 45 per cent of adults said they’d be interested in taking a “safe and effective” prescription drug for weight loss. Meanwhile, seven in 10 adults said they’ve heard at least “a little” about a new class of drugs being used for weight loss, with about one in five saying they have heard “a lot” about these drugs. Ozempic is a type 2 diabetes medication known for its weight loss side effects. Similar semaglutide injections, such as Wegovy and Mounjaro, have been specifically approved for the treatment of obesity and weight loss. This class of drugs called GLP-1 agonists works by mimicking a hormone called glucagon-like peptide 1 (GLP-1), regulating blood sugar levels and slowing down the rate at which food leaves the stomach to create the feeling of fullness. Of the US adults surveyed, older groups were some of the most aware of prescription weight loss drugs, with 76 per cent being those who have been told by a doctor in the past five years that they are overweight or obese. Nearly 60 per cent of those surveyed said they were currently trying to lose weight as well. While there was an overall interest in taking a prescription weight loss drug, that interest significantly decreased when people were asked whether they would take the medication as a routine injection. Only 16 per cent of adults said they would still take Ozempic or Wegovy, even if it wasn’t covered by their health insurance and was not specifically approved by the US Food and Drug Administration for weight loss. In fact, most people believed that insurance companies should cover the cost of weight loss drugs for adults who are overweight or obese, with an overwhelming 80 per cent of adults. Additionally, a large majority of adults believed the substantial profits that pharmaceutical companies have made from increased demand for weight loss drugs is a major factor contributing to the cost of injections like Ozempic and Wegovy. According to Novo Nordisk, the pharmaceutical company behind these prescription drugs for diabetes and weight loss, the list price for Ozempic can cost $935.77 per month without health insurance. Although the majority of adults said they trust pharmaceutical companies like Novo Nordisk to provide “reliable information” about safety and side effects of GLP-1 agonists, only 22 per cent said they trust these companies to price their products fairly. The FDA has listed the most common side effects of taking Wegovy as nausea, diarrhea, vomiting, constipation, abdominal pain, headache, fatigue, indigestion, dizziness, and digestive disorders. More serious complications can occur from use of Wegovy or Mounjaro, such as the “potential risk of thyroid C-cell tumours,” pancreatitis, gallbladder problems, acute kidney injury, increased heart rate, and suicidal behaviour or thinking. Taking Ozempic can also lead to possible thyroid tumours, including cancer, pancreatitis, changes in vision, and kidney and gallbladder problems. Recently, several patients reported suffering from severe gastroparesis, also known as stomach paralysis, after taking the prescription weight loss medications. In a report from CNN, two people claimed that their “stomachs are paralysed” after taking Ozempic. “I wish I never touched it. I wish I’d never heard of it in my life,” Joanie Knight, a 37-year-old from Louisiana, told CNN. “This medicine made my life hell. So much hell. It has cost me money. It cost me a lot of stress; it cost me days and nights and trips with my family. It’s cost me a lot, and it’s not worth it. The price is too high.” One woman was also diagnosed with cyclic vomiting syndrome, which causes her to throw up multiple times a day. “I’ve almost been off Ozempic for a year, but I’m still not back to my normal,” said Emily Wright, a 38-year-old teacher from Toronto. Shortly after the report, the FDA shared in a statement with The Independent that it has become aware of stomach paralysis occurring among patients taking the medications. “The FDA has received reports of gastroparesis with semaglutide and liraglutide, of which some documented the adverse event as not recovered after discontinuation of the respective product at the time of the report,” the agency said. However, officials clarified that they were unable to determine whether taking Ozempic or Wegovy was the cause of stomach paralysis, or if it was caused by a different issue. “Gastroparesis can be a complication of diabetes that is related to long-standing or poorly controlled disease, further complicating the ability to determine what role the drugs played in the reported events,” the FDA added. In response to reports of stomach paralysis, drug manufacturer Novo Nordisk noted that these medications have been used to treat type 2 diabetes “for more than 15 years”, and for the “treatment of obesity” for eight years. “Semaglutide has been extensively examined in robust clinical development programs, large real world evidence studies and has cumulatively over 9.5 million patient years of exposure,” a spokesperson for Novo Nordisk said in a statement to The Independent. “Gastrointestinal (GI) events are well-known side effects of the GLP-1 class. For semaglutide, the majority of GI side effects are mild to moderate in severity and of short duration. GLP-1’s are known to cause a delay in gastric emptying, as noted in the label of each of our GLP-1 RA medications. Symptoms of delayed gastric emptying, nausea and vomiting are listed as side effects.” Read More Obese people on weight-loss jabs ‘should be prepared to stay on them for life’ Ozempic users report stomach paralysis as weight loss drug side effect: ‘I wish I never touched it’ Sharon Osbourne says she was ‘nauseous’ for weeks after taking Ozempic to lose weight Sharon Osbourne reveals what Ozempic did to her when she was taking it Ozempic users report stomach paralysis as side effect: ‘I wish I never touched it’ Lorraine Candy: ‘Perimenopausal rage made me unravel’

Almost a third of people in England and Wales said their mental health has been affected by soaring mortgage costs in the past year, according to new research. For people with existing mental health problems, nearly four in 10 said the rising costs had worsened their mental health. Mind, the UK’s biggest mental health charity, also said it had seen a 55 per cent increase in the number of people contacting its Infoline over the last 18 months about financial difficulties, including welfare, unemployment and personal debt. The charity’s survey of 3,015 respondents across England and Wales in March and April came before Thursday’s news that the Bank of England had raised interest rates to 5.25 per cent from 5 per cent. The hike, which is yet another bid to get inflation under control, will put more pressure on mortgage holders. Mind’s survey – carried out by Censuswide – suggested that 29 per cent of people had been affected by hearing about or experiencing increasing mortgage costs over the last year. Ten per cent said that it had affected their mental health a lot, the charity added. For people with existing mental health problems, some 36% said the increasing mortgage costs had made their mental health worse. The charity said younger people were particularly affected, with almost half (48%) of those aged between 16 and 24 saying that the mortgage situation had impacted on their mental health. Vicki Nash, Mind’s associate director of external affairs, said financial difficulties and mental health problems “often form a vicious cycle”. She said: “As we continue to grapple with the rising cost of living, news of yet another possible increase in mortgage rates will be difficult for many families to bear. “Money problems and mental health often form a vicious cycle, and when we’re struggling to deal with one, the other can become much harder to manage, particularly when it threatens to impact our housing situation. “We know some people are becoming so unwell that they need hospital treatment for their mental health. “When this happens the care they receive when they leave hospital is critical so we are calling for the introduction of comprehensive welfare checks, including of people’s financial situation. “These figures show this is a mental health emergency that everyone is going to need help to deal with. We know we can’t fix the cost-of-living crisis but support for your mental health is out there, and we are here for you. “This includes through Mind’s Infoline, online community, Side by Side and the useful information on our website that will be available throughout this difficult period.” Mind has a confidential information and support line which can be called on 0300 123 3393 between 9am and 6pm from Monday to Friday, or people can visit mind.org.uk. Read More ‘Unsackable’ Jeremy Hunt to remain chancellor as Rishi Sunak eyes ‘election-ready’ Cabinet reshuffle Lizzo: All the allegations made by former dancers – from sexual harassment to body shaming The Bank hikes interest rates again – but the end of the pain could finally be in sight Charity boss speaks out over ‘traumatic’ encounter with royal aide Ukraine war’s heaviest fight rages in east - follow live