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Raven-Symoné has revealed that she underwent several cosmetic surgeries as a teenager, after her father encouraged her to do so while she was receiving criticism about her weight. The That’s So Raven star said she had two breast reductions and liposuction done before she turned 18 in 2004. Speaking on the latest episode of her and her wife Miranda Pearman-Maday’s podcast, Symoné recalled: “There was paperwork involved. My dad suggested strongly that I should get my breasts reduced. “He was like, ‘So you don’t feel bad, is there anything that you want?’ I was like, ‘Yeah, if I get lipo, will people stop calling me fat?’” She continued on The Best Podcast Ever with Raven and Miranda: “So I got a twofer. It was just a mess, just being that young and the pain of it all.” Symoné also disclosed that, after her first breast reduction surgery, she suffered a seizure. “I remember waking up and seeing everything… and then I just started to have this dry mouth and couldn’t breathe and went back under,” she said of the experience. The Cheetah Girls star said she does not remember much else because she was “disassociating” from reality, but admitted that not knowing what caused the seizure “freaks her out a bit”. She still went ahead with the second breast reduction. While she advised others who may be considering similar procedures to wait until they are fully developed before going under the knife, Symoné added that her decision to get breast reductions prevented her “t**ties reaching her ankles”. “I don’t know if I regret it because they grew back not to that big of a size,” she said. Last year, Symoné credited her wife with helping her “kick sugar”, which led to her losing 40 pounds (approximately 18kg). She told The View: “With [Pearman-Maday’s] help and guidance and love and fantastic cooking skills… she helped me kick sugar. “I say ‘kick sugar’ because it is an addictive drug and I was addicted to it in wheat form, in regular form. And it’s out of my system.” Receiving bad news about her health from her doctor also spurred Symoné to take her weight more seriously, so that she could be around longer to spend her life with her wife. “I want to be here for her as long as I can,” she said. “I found out some numbers at the doctor that were not pleasant for someone in my age bracket – or any age bracket, to be honest with you… She doesn’t want to take me to an early grave, and I want to make sure I am there for her in the best health possible.” In July, Symoné called on people not to use diabetes medication Ozempic purely for weight loss, as it is “made for certain people”. She opened up about her family’s history of pre-diabetes and diabetes, and said she is “more susceptible” to the disease if she is not careful about what she eats. “So, I think it’s very important we understand certain medications are made for certain people – and to not take that away just for glamazon purposes,” she told E! News. Read More ‘Oblivious’ woman defended after walking through beach wedding: ‘They don’t own the beach’ Men sometimes need help – and I’m determined to start asking for it King’s Guard shares sweet exchange with young boy wearing royal uniform

Jonnie Irwin has shared an emotional milestone as he cycled with his four-year-old son Rex, on what appeared to be Rex’s last day at nursery. The TV presenter, 49, who is best known for hosting property show A Place in the Sun and Escape to the Country, publicly revealed his diagnosis in November 2022 after his lung cancer spread to his brain. He has previously said he “doesn’t know how long” he has to live. Irwin, who has been receiving palliative care for the past three years, posted an update on Monday (8 August) as he accompanied Rex on his way to nursery. “Last EVER ride to nursery with Rex,” wrote Irwin in a new Instagram post, sharing a series of pictures of himself and Rex on their bicycles as Irwin’s two-year-old son, Rafa, played with a spade. “Suitably waved off by Rafa and his spade and Rex with his game face on!” added Irwin. Irwin, who shares his three boys Rex and twins Rafa and Cormac with his wife Jessica Holmes, detailed his experience of palliative hospice care in a recent interview with BBC Morning Live. The property expert described his hospice experience as a “delight”, adding that his initial perception of such facilities were that they were “very much a boiling hot room full of people who looked frail and towards the end of their days”. However, it was “nothing of the sort” when he did actually go in. “It’s spacious, energised, comfortable,” Irwin told the show, adding: “I’ve had a really, really good experience at my hospice.” He urged anyone who is facing a terminal diagnosis to “embrace” end-of-life care and to try going to a hospice if they have been offered the choice. “My first experience of palliative care and hospice was blood transfusions,” he explained. “I had my first blood transfusion in hospital and then was invited to use the hospice, so I have it a go as a day patient and went into a lovely room. “I implore people to check out hospices. If you’ve got the choice of using it, then use it… I encourage people to explore that option because it’s not the doom and gloom operation you might think it was.” Irwin recently revealed that sometimes he has to “remove himself” from his family home to go to a hospice when he is in a lot of pain because it makes him “not good to be around”. He told Hello! magazine: “I’m like a bear with a sore head and I don’t want [my family] to be around that.” In another appearance with podcast OneChat previously, he said that being in pain affects his mood, explaining: “I have been close to death’s door, twice at least. You lose your memory, you lose your patience. I have got a very short temper. It’s not made me a better person, that’s for sure.” Read More King’s Guard shares sweet exchange with young boy wearing royal uniform ‘Oblivious’ woman defended after walking through beach wedding: ‘They don’t own the beach’ Sandra Bullock’s sister praises actor for being an ‘amazing caretaker’ to late partner Bryan Randall What is ALS and what are the causes? Brain’s appetite control centre different in overweight or obese people – study Areas with lower bird diversity ‘have more mental health hospital admissions’

Sandra Bullock’s longterm partner Bryan Randall has died at the age of 57 after a three-year battle with amyotrophic lateral sclerosis (ASL). His family shared a statement confirming that Randall “passed away peacefully” on Saturday (5 August), adding that he “chose early to keep his journey with ALS private and those of us who cared for him did our best to honour his request”. The statement, sent to People magzine, continued: “We are immensely grateful to the tireless doctors who navigated the landscape of this illness with us and to the astounding nurses who became our roommates, often sacrificing their own families to be with ours.” Bullock and Randall first met in 2015 and made their first public appearance together the following year. The model-turned-photographer’s family has asked for donations to be made to the ALS Association and the Massachusetts General Hospital. ALS affects nerve cells in the brain and spinal cord, its name coming from the Greek and referring to a wasting away of the muscles responsible for controlling voluntary movement caused by a lack of nourishment, the fault of a genetic mutation. As the ALS Association explains: “Motor neurons reach from the brain to the spinal cord and from the spinal cord to the muscles throughout the body. The progressive degeneration of the motor neurons in ALS eventually leads to their demise. “When the motor neurons die, the ability of the brain to initiate and control muscle movement is lost. When voluntary muscle action is progressively affected, people may lose the ability to speak, eat, move and breathe. “The motor nerves affected when you have ALS are the motor neurons that provide voluntary movements and muscle control. Examples of voluntary movements are making the effort to reach for a smartphone or step off a curb. These actions are controlled by the muscles in the arms and legs.” Early symptoms of the disease, according to the US National Institute of Neurological Disorders and Strokes (NINDS), include: muscle twitches in the arm, leg, shoulder or tongue; cramps; tight or stiff muscles; muscle weakness; slurred or nasal speech; and difficulty chewing and swallowing. “The first sign of ALS usually appears in the hand or arm and can show as difficulty with simple tasks such as buttoning a shirt, writing, or turning a key in a lock,” the NINDS explains. “In other cases, symptoms initially affect one leg. People experience awkwardness when walking or running, or they may trip or stumble more often.” There is currently no cure for ALS but the US Food and Drug Administration has approved four drugs to treat the condition and ease the discomfort of sufferers: Riluzole, Nuedexta, Radicava and Tiglutik. It was first discovered by French neurologist Jean-Martin Charcot in 1869 and is also commonly known as Lou Gehrig’s disease in memory of the celebrated New York Yankees baseman (1903-41) who also suffered from it. While ALS affects all demographics, it is most common among people aged between 55 and 75 and, according to some studies, disproportionately affects former members of the armed forces, perhaps because of exposure to harmful toxins during their service careers although this has not been definitively substantiated. The ALS Association reports that, in 90 per cent of cases of ALS, there is no family history of the genetic mutation that causes the disease and, in the 5-10 per cent of cases in which there is, only a 50 per cent possibility exists of its being passed on. For more information, please visit the websites of the ALS Association or the National Institute of Neurological Disorders and Strokes. Read More Roberta Flack announces she has ALS and finds it ‘impossible to sing’ NIH to fund unproven ALS drugs under patient-backed law ALS drug wins FDA approval despite questionable data Brain’s appetite control centre different in overweight or obese people – study Areas with lower bird diversity ‘have more mental health hospital admissions’ Greg Rutherford rushed to hospital ‘screaming and clawing at his skin’

Areas with lower bird diversity appear to have a higher number of hospital admissions related to mental health conditions, research suggests. Experts analysed data from ebird – an online database of bird observations by citizen scientists – to estimate diversity across the US state of Michigan. The team then combined this with hospital admissions for anxiety and mood disorders in the state. The findings, published in the journal Geo: Geography And Environment, showed lower bird diversity to be a significant predictor of higher numbers of hospital admissions for mental health conditions, highlighting the complex relationship between the disorders and biodiversity crises. It is critical we take a holistic approach to our mental health and nature Dr Rachel Buxton The researchers said that while income and the presence of green spaces were the strongest predictors of anxiety and mood disorder-related admissions, there were also independent “significant associations” between mental health and bird diversity. Lead author Dr Rachel Buxton, assistant professor at the Institute of Environmental and Interdisciplinary Sciences at Carleton University in Canada, said: “Often we consider nature as representing the amount of green space near homes or the distance to the nearest park, but the link between species diversity and health is underexplored. “Our study shows that if species diversity can affect mental health at the severe end of the spectrum (hospitalisations), it is possible that the decline in biodiversity across the globe may be intricately connected with our anxiety and mood on a day-to-day basis. “It is critical we take a holistic approach to our mental health and nature. “Investing in nature should not be viewed as a luxury, but a necessity, and evaluated in the context of the support for wellbeing it offers individuals and communities living in urban or nature-scarce environments. “Restoring and conserving diverse bird communities could be one avenue to improving mental health in cities and factored into urban restoration projects and public health policies.” Last year, researchers from King’s College London found that watching birds or listening to birdsong was linked to mental wellbeing, with effects lasting up to eight hours. The Institute of Psychiatry, Psychology & Neuroscience (IoPPN) team said at that time that the links between birds and mental wellbeing were not explained by co-occurring environmental factors such as the presence of trees, plants or waterways.

The brain’s appetite control centre is different in the brains of people who are overweight or live with obesity, a new study suggests. The researchers said their findings add further evidence to the relevance of brain structure to weight and food consumption. Current estimates suggest that more than 1.9 billion people worldwide are either overweight or obese. And, according to the Office for Health Improvement and Disparities, almost two-thirds of adults in the UK are overweight or living with obesity. This increases the risk of developing health issues like type 2 diabetes, heart disease and stroke, cancer and poorer mental health. The last two decades have given us important insights about appetite control and how it may be altered in obesity Professor Paul Fletcher, University of Cambridge A number of factors influence how much people eat and what they eat, including genetics, hormone regulation, and the environment they live in, researchers say. However, it is not entirely clear what happens to the brain to tell us that we are hungry or full. Past studies have shown that the hypothalamus – a small region of the brain about the size of an almond – plays an important role. Dr Stephanie Brown, from the Department of Psychiatry and Lucy Cavendish College, University of Cambridge, said: “Although we know the hypothalamus is important for determining how much we eat, we actually have very little direct information about this brain region in living humans. “That’s because it is very small and hard to make out on traditional MRI brain scans.” Professor Paul Fletcher, the study’s senior author, from the Department of Psychiatry and Clare College, Cambridge, said: “The last two decades have given us important insights about appetite control and how it may be altered in obesity. “Metabolic researchers at Cambridge have played a leading role in this. “Our hope is that, by taking this new approach to analysing brain scans in large datasets, we can further extend this work into humans, ultimately relating these subtle structural brain findings to changes in appetite and eating and generating a more comprehensive understanding of obesity.” The majority of evidence for the role of the hypothalamus in appetite regulation comes from animal studies, which indicate complex interacting pathways within the hypothalamus, with different cell populations acting together to tell us when we are hungry or full. To get around this researchers used an algorithm developed using machine learning to analyse brain scans taken from 1,351 young adults across a range of BMI scores. They looked for differences in the hypothalamus when comparing individuals who are underweight, healthy weight, overweight, or living with obesity. According to the findings, the overall volume of the hypothalamus was significantly larger in the overweight and obese groups of young adults. The researchers describe a significant relationship between volume of the hypothalamus and body mass index (BMI). The differences were most apparent in those sub-regions of the hypothalamus that control appetite through the release of hormones to balance hunger and fullness. While the exact significance of the finding is unclear, one explanation is that the change relates to inflammation, the researchers suggest. Eating a high-fat diet could trigger inflammation of our appetite control centre Dr Stephanie Brown, University of Cambridge Previous animal studies have shown that a high-fat diet can cause inflammation of the hypothalamus, which in turn prompts insulin resistance and obesity. In mice, just three days of a fat-rich diet is enough to cause this inflammation. Other studies have shown that this inflammation can raise the threshold at which animals are full – in other words, they have to eat more food than usual to feel full. Dr Brown added: “If what we see in mice is the case in people, then eating a high-fat diet could trigger inflammation of our appetite control centre. “Over time, this would change our ability to tell when we’ve eaten enough and to how our body processes blood sugar, leading us to put on weight.” More research is needed to confirm whether increased volume in the hypothalamus is a result of being overweight or whether people with larger hypothalami are predisposed to eat more in the first place. It is also possible that these two factors interact with each other, causing a feedback loop, the study published in Neuroimage: Clinical, and supported by the Bernard Wolfe Health Neuroscience Fund, Wellcome and the NIHR Cambridge Biomedical Research Centre, with additional funding from Alzheimer’s Research UK, suggests.

In February a pet dog in Hong Kong tested ‘weak positive‘ for coronavirus and was placed into quarantine. The Agriculture, Fisheries and Conservation Department (AFCD) in Hong Kong confirmed that repeated tests suggested the dog had a “low-level” of the virus and that it was likely to be the case of human-to-animal transmission. The dog, a Pomeranian, had not shown any symptoms for the illness but its owner was confirmed as being infected with Covid-19. Now pet owners are becoming increasingly concerned they could catch the deadly disease from their animals - but is that scientifically possible? Can I catch coronavirus from my pet? On 2 April a Chinese study showed that cats are "highly susceptible" to coronavirus and it can easily be passed between them. But only five cats were involved in the experiment. This follows the news that a cat reportedly contracted coronavirus in Belgium but health authorities in the country said it was an "isolated case" and not "the rule". There are still no reports of animals in the UK with coronavirus. On 13 March the World Health Organisation said "at present there is no evidence that companion animals/pets such as dogs or cats can be infected with the new coronavirus". Several global health organisations have issued advisories saying there is no any evidence that pet animals can spread coronavirus or indeed be infected with it in the same way as humans. “Therefore, there is no justification in taking measures against companion animals which may compromise their welfare,” the World Organisation for Animal Health has said. The Centers for Disease Control and Prevention concurred that “there is no reason to think that any animals including pets in the United States might be a source of infection with this new coronavirus”. Raymond R.R. Rowland, a veterinarian who specialises in swine viruses at Kansas State University, said that “weak positives” frequently show up in testing pigs, where a farmer’s livelihood can be at stake. “I’ll tell you what I tell them,” he told The New York Times. “Wait and see.” Even if the Pomeranian has a low-level infection, he said: “that doesn’t say the animal is sufficiently infected that it can spread the virus.” The dog could simply be a host for the illness that neither becomes unwell or infects other people or animals. Should I change my behaviour with my pet? The World Health Organisation says: "It is always a good idea to wash your hands with soap and water after contact with pets. “This protects you against various common bacteria such as E.coli and Salmonella that can pass between pets and humans.” To protect yourself from catching coronavirus, the WHO advises the following: Cover your mouth and nose while sneezing, with a tissue or your elbow Put the tissue straight into a closed bin Wash your hands afterwards, and then frequently, with soap or sanitiser Keep your distance from people who are coughing and sneezing (at least one metre) [[Updated UK government advice also says people should stay at home and practice social distancing]. You can read more about the WHO’s advice on coronavirus here. Read More What are symptoms of coronavirus – and where has it spread? Latest travel updates as coronavirus continues to spread Can face masks really protect you against coronavirus or flu? The dirty truth about washing your hands Greg Rutherford had mystery allergy left him ‘screaming and clawing at his skin’ What is Lyme disease? Bella Hadid reveals ’15 years of invisible suffering’ Study reveals how muscle cells deteriorate with age, hampering injury recovery

Greg Rutherford’s fiancée Susie Verrill has shared that she had to rush the British track and field athlete to the hospital on Saturday (5 August) after an unknown illness left him “clawing at his skin and just screaming”. Verrill, a social media influencer and blogger, posted about the incident on her Instagram page on Monday morning (7 August) and described it as the “scariest time” of her life. Alongside a photograph of Rutherford, 36, sitting up in a hospital bed and appearing to grimace, she explained that the day began normally and that she went to their friend’s house for a roast dinner with their three children. Verrill said she later received a text message from Rutherford informing her that he might be having “an allergic reaction to something and felt itchy”, but she did not think it was an emergency. However, he called shortly after “screaming” on the phone, she wrote, adding: “And I mean SCREAMING. He shouted, ‘YOU NEED TO GET HERE NOW’ and so I drove back to our house while calling an ambulance, terrified I was about to get home and find him not breathing.” The blogger said she was told that an ambulance would take 40 minutes. Once home, she “ran into the house” and found Rutherford inside, “screaming” and “acting like one of those people you see in videos where they’ve taken bath salts”. “He was clawing at his skin and just screaming. Repeatedly. He ran to our car and while I rang 999 again to say I’d have to take him, we had to run every red light and I had to focus on not crashing while he screamed and tried to grab the wheel,” she recalled. “He was delirious and I looked like I was kidnapping him. I was on the phone to the 999 call handler and the poor girl just kept saying, ‘OK yeah he doesn’t sound good, please be safe but hurry’ and I was like OK well this is a nightmare because I’ve been driving like three months. It was AWFUL.” She continued her story in another slide, which showed a close-up of Rutherford’s skin on his thighs. It appeared red with raised bumps, like hives or a rash, covering the surface. Verrill said she “threw [Rutherford] out” of the car in front of the A&E and went to park her car. Once inside the hospital, she was told that staff had sent him to “Resus”, which is a term used for the resuscitation area of the department. “I think [they sent him there] mainly because he was a six-foot-three bloke acting like a psychopath and they didn’t want to scare anyone,” she wrote, adding: “They also pumped him full of steroids and antihistamines and it seemed to work pretty much immediately. Thankfully by the time I got there he’d stopped screaming and raking himself.” In the next slide, she showed Rutherford still sitting up in a hospital bed, but appearing calmer. She said that they were allowed to leave the hospital three hours after they arrived. Verrill added that she “felt close to having a heart attack” but reassured followers that she was fine otherwise. “My question is – we did nothing differently yesterday in terms of eating/drinking but the only snack Greg ate was nuts – could he have developed an allergy, do we think?” she asked her fans. “Have any of you had this? Hospital recommended we get him tested but said it could have also been viral. I appreciate rashes can appear with a viral illness but his body went MAD. The doctor who suggested the viral thing hadn’t seen how Greg had been on arrival; I can’t explain how much pain he was in.” She recalled a time when Rutherford “shrugged off a grumbling appendix” in comparison to how he reacted to the recent illness, and asked followers to let her know if they had ever experienced something similar. In her most recent Instagram Story, Verrill addressed suggestions from fans that Rutherford may have come into contact with a plant on his run that may have caused the reaction. “We don’t think it was any sort of plant because the reaction began before he went on his run (although we appreciate this may have exacerbated symptoms with the sweating),” she wrote. “Greg’s having some tests this morning so hopefully it can start the ball rolling and if I don’t get back to you just yet, I’m so sorry. I’ve had about 500 messages already! Really, really appreciate all the advice.” Rutherford, who participated in Strictly Come Dancing in 2016, also shared Instagram Stories about his experience. In one slide, showing a close-up of his skin from another angle, he wrote: “I suddenly had a massive allergic reaction to something (no idea what) and had to get Susie to rush me to hospital. Thankfully they pumped me with a load of stuff and calmed it down. But it was HORRIBLE. This rash was covering my entire body.” In a second Story, he shared a photograph of himself and added: “I’m not home. A little [itchy] still, but nothing like earlier. I was trying to get my skin off it was so bad. I’m going to get some tests done to figure out what it was, as I NEVER want to experience that again.” The sportsman thanked the hospital staff for helping him, adding: “I was screaming at one point… So apologies for that too.” Rutherford and Verrill have been together since 2012 and share a daughter named Daphne, two, and sons Milo and Rex, eight and five respectively. The couple were due to be married in May, but postponed their wedding because of the death of a family member. Read More Marina O’Loughlin is wrong – there’s joy in solo dining Jamie Foxx and Jennifer Aniston issue statements over ‘antisemitic’ Instagram post Will Smith says daughter Willow’s ‘mutiny’ changed his view on success What is Lyme disease? Bella Hadid reveals ’15 years of invisible suffering’ Study reveals how muscle cells deteriorate with age, hampering injury recovery Bella Hadid looks back on ‘15 years of invisible suffering’ with Lyme disease

Model Bella Hadid recently shared an update on TikTok, that her Lyme disease symptoms had flared up following a tooth infection. The Dutch-Palestinian 26-year-old was diagnosed with Lyme disease in 2012, and in her latest health update, shared she was struggling with its symptoms once again. “There was a low-grade infection underneath the tooth, next to the tooth I thought was suffering (she’s good) which is the one I got a root canal on a year ago. It continued to spread down, causing a low-grade infection in my jaw,” Hadid shared on TikTok. She continued by saying: “Please listen to your bodies my friends! This made my Lyme flare up, which means the Lyme is attacking the places that are suffering i.e. tooth, jaw, gut, brain, spine, bones etc oh, and the entire nervous system.” So, what is Lyme disease? “Lyme disease is an infection caused by a group of bacteria transmitted through an infected tick, giving you a specific set of symptoms,” says Dr Sanjay Mehta, GP at the London General Practice. According to analysis published in the open access journal BMJ Global Health, more than 14% of the world’s population probably has, or has had, tick-borne Lyme disease. But Mehta says you can’t catch it from any tick, only infected ones. The disease can also be seasonal – “It doesn’t die down to zero, but it drops significantly during summer and winter, and peaks during early autumn and spring,” he says. What are the symptoms? Lyme disease can manifest in a variety of different ways – from being asymptomatic, to nerve damage, in more severe cases. “There are two main groups of patients,” says Mehta. “First, there’s the group who catch it early, and they don’t really get any symptoms – they just see they’ve been infected by a tick. “Then there’s the second group of people who don’t get treatment, and although only a very small percentage of them actually end up with symptoms, they are the ones we worry about. “Those patients tend to get three stages of symptoms. First, they might get flu-like symptoms kicking in a week or so after the bite, and a characteristic rash. Second, some might then get symptoms related to their nerves, their heart and their brain, several weeks or months later. “An even smaller number of people might then get the third stage, and these are the symptoms people typically associate with Lyme disease – long-term joint problems and neurological symptoms.” How do you contract Lyme disease? As Lyme disease is passed on exclusively via infected ticks, you can downgrade the disease from unlikely to highly unlikely by avoiding tick-heavy areas or taking precautions within them. “There are areas of the UK known to harbour infected ticks, like the Lake District, the New Forest, the North York Moors, and the Scottish Highlands,” says Mehta. “If you see ticks on your skin, you don’t necessarily get transmission for up to four hours, so if you can remove them, that’s ideal.” If you are going to any of these areas, there are also a few simple things you can do to limit the risk. “Try to keep to paths in grassy, wooded areas, and keep away from long grass and vegetation,” advises Mehta. “It sounds obvious, but shower on your return – often ticks fall off – and check yourself for them too. Wear insect repellent, long T-shirts, and long trousers if possible.” What should you do if you get bitten? The simple answer is, if you’ve gone to a high-risk area and you know you’ve been bitten by something, see a doctor. “It is worth going on to treatment, which is a course of specific antibiotics,” says Mehta. “We do run tests, and the tests are fairly reliable, but the main things are a) have you gone to a risky area? b) have you seen you’ve been bitten? And c) have you developed symptoms?” “The take-home message is to seek medical help if there is a bite, but be aware, it’s only a small percentage of people who end up with problems.” Read More Charity boss speaks out over ‘traumatic’ encounter with royal aide Ukraine war’s heaviest fight rages in east - follow live Study reveals how muscle cells deteriorate with age, hampering injury recovery Tips and tricks to preserve your harvest Is it heat exhaustion or are you just tired?

Researchers have revealed how muscle cells deteriorate with age, affecting their ability to regenerate and recover after an injury. The findings could help to shed light on why it takes people longer to recover from muscle damage as they age. A team at Nottingham Trent University analysed the genes inside muscle cells, and found the ‘development pathways’ – the different ways in which genes work together to regenerate muscle – become weakened in older cells. We know that healthy muscle regenerates after we’ve had an injury but ageing impairs that regeneration potential and recovery gets harder the older we get Dr Livia Santos, Nottingham Trent University Lead researcher Dr Livia Santos, an expert in musculoskeletal biology in Nottingham Trent University’s School of Science and Technology, said: “This goes some way towards explaining why muscle injuries may take longer to recover as we get older.” She added: “We know that healthy muscle regenerates after we’ve had an injury but ageing impairs that regeneration potential and recovery gets harder the older we get. “What we’ve observed, in terms of what happens inside the cells, helps us to better understand why we don’t heal as well or as quickly in older age. “The pathways that control cell processes and development work differently in older cells and are downregulated, meaning regeneration is impacted the older we get. “If we can understand these pathways, however, we could potentially identify new therapies and interventions to mitigate the problem.” The researchers developed a new approach to examine muscle cells in the laboratory to enable them to observe the different mechanisms that drive muscle ageing. They studied muscle cells from donors, chemically injuring cells after they had been donated and isolated, then assessing how they heal and regenerate back to their pre-injury baseline levels. When they looked at cells from a 20-year-old and a 68-year-old donor, researchers found distinct differences in the development pathways of the younger and older cells. While younger muscle cells fully recovered from the injury, the team found that in older cells the genes expressed less of what they needed to, leaving the cells no longer able to perform in the way they should. According to the researchers, this contributes to reduced regeneration capacity leading to thinner, less robust ‘myotubes’ – a type of cell that can fully develop into a muscle fibre. Muscle regeneration is a complex and finely balanced biological process and is known to deteriorate with ageing, leading to the decline of musculoskeletal health and in some cases metabolic and genetic diseases. Our work enables us to examine muscle cell regeneration across the lifespan and this in turn could be key for future drug discovery for disease related to muscle ageing Researcher Janelle Tarum Janelle Tarum, another researcher on the study, said: “We’ve been able to develop a new approach to assess muscle regeneration which involves a state-of-the-art technique called RNA-sequencing. “There’s a very clear reduced regeneration capacity and weakened recovery of aged cells and we have been able to further understand the factors underlying this impairment. “Our work enables us to examine muscle cell regeneration across the lifespan and this in turn could be key for future drug discovery for disease related to muscle ageing.” The study, which also involved Manchester Metropolitan University and Liverpool John Moores University, is published in the Journal of Tissue Engineering and Regenerative Medicine.

Bella Hadid has shared a candid post reflecting on her health journey as she has lived with Lyme disease since 2012. The 26-year-old supermodel shared a health update with her 59.3 million followers on Instagram on Sunday (6 August) and said she is “finally healthy” after more than a decade of struggling with her health. She shared a number of photographs taken during her treatments over the years, showing her receiving drips and injections, laying in hospital beds as nurses gave her medication, and health documents from her medical record. In her lengthy caption, Hadid wrote: “The little me that suffered would be so proud of grown me for not giving up on myself. Living in this state, worsening with time and work while trying to make myself, my family and the people who support me, proud, has taken a toll on me in ways I can’t really explain.” “To be that sad and sick with the most blessings/privilege opportunity/love around me was quite possibly the most confusing thing ever,” she reflected. She reassured fans that she was “OK and you do not have to worry”, and said that despite her struggles, she “wouldn’t change anything for the world”. “If I had to go through all of this again, to get here, to this exact moment I’m in right now, with all of you, finally healthy, I would do it all again. It made me who I am today,” Hadid continued. The model, who was named one of Time magazine’s 100 most influential people in the world this year, “promised” fans who were also struggling that things “will get better”. “Take a step away, stay strong, have faith in your path, walk your truth and the clouds will start to clear up,” she wrote. “I have so much gratitude for and perspective on life, this 100+ days of Lyme, chronic disease, [co-infection] treatment, almost 15 years of invisible suffering, was all worth it if I’m able to, God-willing, have a lifetime of spreading love from a full cup and being able to truly be myself, for the first time ever.” Hadid explained that she chose photos that were “the most positive” throughout her health journey in an attempt to illustrate how it has been “the most enlightening experience of my life filled with new friends, new visions and a new brain”. She thanked her mother, Yolanda Hadid, who was also diagnosed with Lyme disease in 2012 alongside her son and Hadid’s younger brother Anwar, for “keeping all of my medical records, sticking by me, never leaving my side, supporting, but most of all, believing me through all of this”. Hadid also thanked the brands and companies she has worked with, her agents for “protecting me”, and her medical team, adding: “I love you SO much!!!” She told fans that she would be “back when I’m ready”, adding: “I miss you all so much. I love you all so much.” Lyme disease is a bacterial infection that can be spread to humans by infected ticks and if usually diagnosed based on symptoms, which include fever, headache, fatigue or skin rash, or laboratory testing. Earlier this year, Hadid spoke about some of the symptoms she gets when her Lyme disease flares up. In a TikTok video, she said: “My skin changes colour, I break out randomly, I get (what feels like) lesions, lethargy, chronic anxiety, zero motivation or purpose, leaky gut, adrenals, depression.” She added that she “hates looking in the mirror or taking pictures” of herself because of how the disease impacts her appearance. “If I’m all dolled up, maybe I’ll try for the girls but, man, is it hard to do this as your profession while also feeling/looking sick like this,” she said. Read More Doing things alone isn’t ‘self-love’ – we don’t need to make everything empowering Jamie Foxx and Jennifer Aniston issue statements over ‘antisemitic’ Instagram post Will Smith says daughter Willow’s ‘mutiny’ changed his view on success Is it heat exhaustion or are you just tired? Will Smith says Willow ‘mutiny’ changed his view on family success Health expert Dr Michael Mosley shares two tips for avoiding osteoporosis

Whether you’re away on holiday or lounging in the sun at home, needing a siesta after lunch or a disco nap before dinner on a hot summer’s day is normal. But how can you tell when warm weather-induced drowsiness is something more serious? We asked doctors to explain… What is heat exhaustion? “Prolonged exposure to the heat can cause heat exhaustion. It is the body’s response to excessive loss of water and salt,” says Dr Preethi Daniel, deputy medical director at London Doctors Clinic. “Symptoms may be characterised by heavy sweating, rapid breathing, headache, high temperature, nausea, a faster and weak pulse, light-headedness, feeling fatigued and heat cramps.” Older people, babies, children and those with chronic illnesses are much more likely to develop heat exhaustion. “Symptoms are usually the same in adults and children, and can make children tired and floppy,” says Dr Luke Powles, associate clinical director at Bupa Health Clinics. While not life-threatening, heat exhaustion is a warning sign that you need to cool down promptly to prevent progression to heat stroke, which means getting out of the sun immediately. “Remove any unnecessary clothing, lie down and raise your feet so they are above the level of your heart and drink plenty of water,” says Powles. “You can also use a cool sponge to cool your skin. Make sure someone stays with you until you feel a bit better – which you should do in half an hour or so.” If you don’t start to cool down after 30 minutes, see medical help, as you may have developed heatstroke. What is the difference between heat exhaustion and tiredness? “Heat exhaustion is the direct result of spending too much time in the sun and often raises your core body temperature to over 38 degrees, which isn’t an indicator of general tiredness,” says Dr Carolyn Barshall, GP at independent charitable hospital King Edward VII’s. “Whereas tiredness can be caused by many lifestyle factors such as disordered sleeping patterns, alcohol and poor diet.” Daniel adds: “If you have a lack of energy or aches and pains, consider it tiredness, but if you have any of the other symptoms mentioned above, it could be heat exhaustion.” What is heatstroke? “Heatstroke is the end result of overheating,” says Daniel. “Our internal temperature rises and creates confusion, drowsiness and can lead to seizures.” Much more serious than heat exhaustion, it can cause a change in mental status such as, Barshall says: “Confusion, delirium, combativeness, seizures, loss of consciousness, and a core body temperature above 40 degrees.” Symptoms may also include skin that’s not sweating even when it feels hot, fast breathing or shortness of breath. “Heat exhaustion and heatstroke are often confused, but there is a difference,” says Powles. “Heatstroke should be treated as an emergency, whereas with heat exhaustion, the person needs to be cooled down.” If you suspect someone has heatstroke you should call 999 or seek emergency help immediately. How to stay safe in the sun To prevent heat exhaustion during summer, it’s important not to spend too long in the sun and to stay hydrated. “Avoid direct sunlight between 11am and 3pm, and wear light-coloured, loose clothing,” says Daniel. “Drink plenty of cold drinks and water throughout the day and limit alcohol intake.” To help little ones, she says: “You can keep a pram or buggy cool by covering it with a damp cloth and refreshing it every 30 minutes.” Read More Charity boss speaks out over ‘traumatic’ encounter with royal aide Ukraine war’s heaviest fight rages in east - follow live King Charles enjoys a wee dram at the Met Highland Gamesv Why have the birds disappeared from my garden? Top Films: w/c Saturday, August 12

Health “guru” Dr Michael Mosley has offered his advice to those seeking to reduce their risk of developing osteoporosis, a condition characterised by weak or brittle bones. The medical expert and former doctor is known for his regular appearances on The One Show, as well as his TV programmes on health and medicine. Writing in his column for MailOnline, the creator of the 5:2 and Fast800 diets said he had found his bones were not as strong as they could be while filming a series about healthy ageing in 2022. “Like many Britons, my bones are weaker than they should be,” he wrote. “While filming a series about healthy ageing last year, I had a DXA scan, which uses low-dose X-rays to see how dense (or strong) your bones are. “Although I have a sturdy spine, my hip bones aren’t in great shape, though I don’t have osteoporosis.” Dr Mosley explained that the key to avoiding osteoporis involves getting a healthy intake of both calcium and Vitamin D, as well as a short but effective burst of exercise each day. “As well as obvious good calcium sources such as dairy and leafy green veg, you may want to top up on prunes,” he suggetsed. “A study last October in the American Journal of Clinical Nutrition, involing 235 older women, concluded eating five to six prunes a day improved bone density. The theory is that anti-inflammatory compounds in prunes may slow bone breakdown.” He also suggested that daily exercise could also help, citing a study that showed two minutes of hopping each day can improve hip bone strength. In 2020, Dr Mosley claimed that men were “more deluded” than women when it came to their own weight and fitness, while fronting a Channel 4 series to help people who had gained weight during lockdown. He told the Press Association: “An awful lot of people are unaware of how much weight they put on, particularly around the gut.” Research shows that only 10 per cent of people who are obese know they are but that the figure is only 7 per cent for men, Dr Mosley said, while “women are more aware of it”. He also denied that the show, which offers practical advice to overhaul viewers’ lifestyles, was about fat shaming: “Body shaming is awful. It is incredibly ineffective. Telling people they’re fat never, ever works,” he said. “None of this is about fat-shaming. It is entirely about helping people who are obese and who want to do something about it. Any diet is only ever going to work if the person wants to do it.” Read More Jamie Foxx and Jennifer Aniston issue statements over ‘antisemitic’ Instagram post Why is every celebrity couple breaking up? Relationship experts think we shouldn’t be so shocked Eye masks, kombucha and ‘the full spectrum of milks’: Gwyneth Paltrow finally gave us a tour of her fridge Health expert Dr Michael Mosley shares two tips for avoiding osteoporosis Will Smith says Willow ‘mutiny’ changed his view on family success Who was controversial vegan raw food influencer Zhanna D’Art: