List of All Articles with Tag 'c'

Danish drugmaker Novo Nordisk A/S on Friday surpassed French luxury powerhouse LVMH to become Europe’s most valuable company,

A wave of strikes and the collapse of a major carrier took a toll on US payroll growth

Walgreens Boots Alliance on Friday said that CEO Rosalind Brewer has stepped down less than three years after taking the helm at the pharmacy chain.

MALVERN, Pa.--(BUSINESS WIRE)--Sep 1, 2023--

Khloe Kardashian has officially changed her son Tatum’s last name, one year after his birth. A Los Angeles county judge granted the name change for the baby – who Kardashian shares with ex Tristan Thompson – on 31 August, according to documents obtained by US Weekly. In June, the publication had first reported that Tatum’s last name was initially listed as “Kardashian” on his birth certificate. Now, the 13-month old has been granted a new surname, which is the same as his father’s, officially decreeing him “Tatum Thompson”. Similar to law in other states, California law allows parents to pick if they want their child to have their father or mother’s last name. Parents can also do the combination of the two, and give the baby a surname with a hyphen in between the two last names. The law states that whatever last name is picked will be permanent, as a court order is required to change the name. In July 2022, the former couple welcomed their child, Tatum, together via surrogate. They also share a five-year-old daughter, True. The arrival of the pair’s second baby came months after they ended their on-and-off relationship, when Thompson confirmed he fathered a son with fitness instructor Maralee Nichols. In the most recent season of The Kardashians, the Good American founder has also spoken candidly about raising her son. During an episode of season three, which aired in June, she admitted to feeling less bonded to her son born via surrogacy than her daughter True, who she birthed herself. “With True, it took me a couple of days to be like, okay, this is my daughter,” Kardashian said. “With him, it’s taken me months. I love him and I love kids but, I still don’t have that complete bond.” Kardashian added that she sometimes felt “guilty” that she hadn’t bonded with her son in the same way as her daughter. “I’m like, why isn’t it the same? But I know it will be and I know, like, I don’t treat him differently. I just question myself sometimes,” she explained. Despite her challenges and feelings about her son, Kardashian also acknowledged that she was being hard on herself. “I wish I wasn’t so critical of myself because I’m very kind to everyone else,” Kardashian said in her confessional. “I’m just not very kind to myself.” “But being a mom is truly one of the most magical experiences ever,” she added. In July, Kardashian took to Instagram to share a series of photos of Tatum in honour of his first birthday. She also included a sweet tribute about her relationship with her son, in which she expressed how ​“God knew [her] heart needed” him when he was born. “I am so proud to be your mommy. So proud of the love and laughter we have in our house. So proud of your beautiful, gentle, loving, infectious spirit. You light up every single room. There’s no denying that everyone smiles when they look at you!” she wrote. “Especially True, she is so proud to call you hers.” Read More Khloe Kardashian denies disrespecting Halle Berry and says ‘don’t tear me apart’ amid Tristan Thompson reports Khloe Kardashian reveals ex Tristan Thompson and his brother moved in with her after their mother died Kylie Jenner addresses the ‘misconceptions’ she’s had plastic surgery Khloe Kardashian officially changes son Tatum’s last name to Thompson Khloe Kardashian takes swipe at ‘hater’ for insulting sister Kim How did man who dodged theme parks due to his weight lose nearly 60kg?

Food ads have long made their subjects look bigger, juicier and crispier than they are in real life

Legal and regulatory hurdles for people offering their homes for short-term rental on sites like Airbnb Inc. and

This week’s new entertainment releases include an album from the 20-member K-pop super group NCT, ”Indiana Jones and the Dial of Destiny” swings into streaming

You don't need a grill—or a backyard—to enjoy barbecue season.

Welcome to Social Buzz, a daily column looking at what’s trending on social media platforms. I’m Caitlin Fichtel,

Alcohol addiction ruins millions of lives every year, but scientists may have found a cure for this terrible affliction. A new treatment for alcohol use disorder (AUD) has been trialled in monkeys with impressive results and, if these translate to human trials, the impact could be monumental. A team of neuroscientists and physiologists from across the US tested a new type of gene therapy to see if they could directly target the underlying brain circuitry associated with sustained heavy drinking. As they noted, in the journal Nature Medicine, people suffering from AUD commonly return to alcohol use even if they attempt to quit. This is largely to do with what’s known as mesolimbic dopamine (DA) signalling – meaning how the central nervous system circuit communicates the feelgood neurotransmitter dopamine. A protein called glial-derived neurotrophic factor (GDNF) is key to keeping these neurons in this reward circuitry functioning. However, experts have found that levels of GDNF are reduced in people with AUD during periods of alcohol abstinence, most notably in a region of the brain called the ventral tegmental area (VTA), as IFLScience notes. Therefore, the researchers decided to test whether using gene therapy to deliver more GDNF to the VTA could help reinforce this crucial dopaminergic signalling and prevent patients from suffering an alcoholic relapse. The team of scientists explained how alcohol consumption in non-addicts prompts the release of dopamine, creating a pleasurable buzz feeling, but chronic alcohol use causes the brain to adapt and stop releasing so much dopamine. “So when people are addicted to alcohol, they don’t really feel more pleasure in drinking,” Dr Kathleen Grant, a senior co-author of the study, said in a statement. “It seems that they’re drinking more because they feel a need to maintain an intoxicated state.” For their research, Dr Grant and her colleagues used eight rhesus macaque monkeys, who were exposed to increasing concentrations of alcohol over four 30-day “induction” periods. The monkeys then had free access to alcohol and water for 21 hours a day for six months, during which they developed heavy drinking behaviours. This was then followed by a 12-week abstinence phase, with the GDNF treatment performed four weeks in for half of the subjects. The gene therapy was delivered using a a viral vector containing a copy of the human GDNF gene injected directly into the primate’s VTA, according to IFLScience. And the results were truly jaw-dropping. “Drinking went down to almost zero,” Dr Grant said. “For months on end, these animals would choose to drink water and just avoid drinking alcohol altogether. They decreased their drinking to the point that it was so low we didn’t record a blood-alcohol level.” The most exciting aspect of their findings is the suggestion that gene therapy could offer a permanent solution for people with the most severe cases of AUD. This will be a welcome glimmer of hope to many, given that some 29.5 million people were diagnosed with AUD in the US alone in 2021, according to the National Institute on Alcohol Abuse and Alcoholism. Of these 29.5 million sufferers, almost a million (894,000) were aged between 12 and 17. It’ll likely be some time before we know for sure whether the gene therapy can be rolled out in humans, but it’s an important first step in tackling this devastating disorder. Sign up for our free Indy100 weekly newsletter Have your say in our news democracy. Click the upvote icon at the top of the page to help raise this article through the indy100 rankings.

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