Wednesday and Thursday are the last two days of Manhattanhenge

One of the most prominent pro-Palestine accounts, with over six million followers on Instagram, has

Amazon Prime Day is finally upon us and exciting deals await on electronics, clothes, makeup

LGBTQ+ revelers and allies are partying coast to coast for the grand crescendo of Pride Month

We’ve come a long way since personal shoppers sashayed about department store floors with extremely well-lit designer wares filling walls and floor space. Nowadays, splurging on a new “it” bag or gown is as easy as 1, 2, order confirmed. And don’t get me wrong: I love an ~experience~ as much as the next gal, but in the year 2023? It’s hard to argue with the convenience of online shopping. (Also, it’s kind of our thing.)

TORONTO--(BUSINESS WIRE)--Sep 7, 2023--

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Parkinson’s disease is the world’s second most common neurodegenerative disorder, behind Alzheimer’s disease. While it’s unknown exactly why people develop the condition, according to Parkinson’s UK, experts believe its a combination of genetic and environmental factors that contribute to the damage of nerve cells in the brain. So what are the symptoms of Parkinson’s disease and how can it be treated? Here’s everything you need to know. What is Parkinson’s disease? Parkinson’s disease is a degenerative neurological condition. This means that over time the brain of an individual living with the disease becomes more damaged, the NHS explains. A person living with Parkinson’s disease doesn’t have enough of the chemical dopamine in their brain, the Parkinson’s Foundation states. Dopamine is responsible for transmitting signals between nerve cells in the brain. When an individual experiences a loss of nerve cells in the brain, this causes a reduction in the quantity of dopamine in the brain. What are the symptoms? The main symptoms of Parkinson’s disease include involuntary shaking (otherwise known as tremors), movement that’s slower than usual and stiffness in the muscles, the NHS outlines. Other symptoms may include difficulty balancing, nerve pain, incontinence, insomnia, excessive sweating, depression and anxiety. For more information about the symptoms of Parkinson’s disease, visit the NHS here. How many people does it affect? Around 145,000 people in the UK are affected by Parkinson’s disease, Parkinson’s UK explains. This means that around one in every 350 adults is living with the degenerative condition. According to the NHS, symptoms of Parkinson’s usually develop after the age of 50. However, for every one in 20 people affected by the disease, symptoms may appear when they’re under the age of 40. The Parkinson’s Foundation outlines that men are 1.5 more likely than women to be affected by the condition. High-profile individuals to have been diagnosed with Parkinson’s include former US president George H. W. Bush, Back to the Future star Michael J. Fox and The Chase star Paul Sinha. How can it be treated? While there is no known cure for Parkinson’s disease, symptoms may be controlled through treatment. The most common form of treatment used for the condition is medication, Parkinson’s UK states. “Drug treatments aim to increase the level of dopamine that reaches the brain and stimulate the parts of the brain where dopamine works,” the charity explains. The medication used to treat Parkinson’s disease varies according to each patient. This is because as symptoms of the disorder progress, the drugs used to treat the condition may need to be changed. While drug treatment may help to manage Parkinson’s symptoms, it cannot slow the progression of the disease. The NHS explains that those living with Parkinson’s disease may also undergo physiotherapy, occupational therapy, and, in rare cases, brain surgery to treat the condition. For more information about Parkinson’s disease, visit Parkinson’s UK. Read More What are symptoms of coronavirus – and where has it spread? Latest travel updates as coronavirus continues to spread Can face masks really protect you against coronavirus or flu? The dirty truth about washing your hands Billy Connolly shares health update on Parkinson’s disease: ‘Every day gets stranger’ Tracey Emin says she ‘totally accepted death’ following cancer diagnosis Nicky Hilton calls out critics who made negative comments about nephew Phoenix’s head

Using existing drugs to treat cervical cancer before standard treatment could lead to a 35% reduction in the risk of relapse or death, a new study suggests. Researchers from the UCL Cancer Institute and UCLH looked into whether a short course of induction chemotherapy (IC), where a drug is used to destroy as many cancer cells as possible, before chemoradiation (CRT), could help with this. Here’s everything you need to know about the findings… What is cervical cancer? According to the NHS website, cervical cancer is a type of cancer found anywhere near the cervix – the opening between the vagina and the womb (uterus), which is also known as the neck of the womb. Most cervical cancers grow very slowly and are caused by an infection from specific types of human papillomavirus (HPV) and mostly affect women under the age of 45. According to Jo’s Cervical Cancer Trust, symptoms include vaginal bleeding that is unusual to you, changes to vaginal discharge, discomfort during sex and pain in your lower back or pelvis. Changes to cells can be spotted by a cervical screening, and then treated before they turn into cancer. There are around 3,200 new cases every year in the UK, with the five-year survival rate being around 70%, according to Cancer Research UK. CRT has been the standard treatment for cervical cancer patients since 1999, but even though there have been overall significant developments in radiation therapy techniques, up to 30% of people experience their cancer coming back. What did the research involve? Over a 10-year period, 500 patients who had been diagnosed with cervical cancer – that was large enough to see without a microscope but hadn’t spread to other parts of the body – took part in the Interlace trial at hospitals in the UK, Mexico, India, Italy and Brazil. Researchers looked into whether a short course of IC before CRT could reduce rates of relapse and death. What results were found? After five years, researchers discovered that 80% of the people who received a combination of chemotherapy and radiotherapy were alive, whilst 73% had not seen their cancer return or spread. A major benefit, according to researchers, is that it can be incorporated into standard of care treatment relatively quickly, because cheap, accessible and already-approved ingredients such as carboplatin and paclitaxel are needed for IC. “Our trial shows that this short course of additional chemotherapy delivered immediately before the standard CRT can reduce the risk of the cancer returning or death by 35%,” said Dr Mary McCormack, lead investigator of the trial from UCL Cancer Institute and UCLH. “This is the biggest improvement in outcome in this disease in over 20 years. “I’m incredibly proud of all the patients who participated in the trial; their contribution has allowed us to gather the evidence needed to improve treatment of cervical cancer patients everywhere. “We couldn’t have done this without the generous support of Cancer Research UK.” Why is the research important? Dr Iain Foulkes, executive director of research and innovation at Cancer Research UK, said: “Timing is everything when you’re treating cancer. The simple act of adding induction chemotherapy to the start of chemoradiation treatment for cervical cancer has delivered remarkable results in this trial. “A growing body of evidence is showing the value of additional rounds of chemotherapy before other treatments like surgery and radiotherapy in several other cancers. “Not only can it reduce the chances of cancer coming back, it can be delivered quickly using drugs already available worldwide. “We’re excited for the improvements this trial could bring to cervical cancer treatment and hope short courses of induction chemotherapy will be rapidly adopted in the clinic.”