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Women with myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) tend to have more symptoms and co-occurring conditions than men, according to the world’s largest study of the disease. The study, entitled DecodeME, reveals women who have the condition for more than 10 years are more likely to experience increasingly severe symptoms as they get older. ME/CFS is estimated to affect more than 250,000 people in the UK, of all ages and from all social and economic backgrounds. Its key feature, called post-exertional malaise, is a delayed dramatic worsening of symptoms following minor physical effort. Other symptoms include pain, brain fog and extreme energy limitation that does not improve with rest. Causes are unknown and there is currently no diagnostic test or cure. Experts from the University of Edinburgh analysed anonymous survey questionnaires from more than 17,000 people with ME/CFS. Two-thirds of women, and slightly more than half of men, reported at least one active co-occurring condition. Similarly, 39.2% of women and 28.6% of men reported at least one inactive co-occurring condition. We discovered that the disease is worse for women, in older people, and many years after their ME/CFS started Professor Chris Ponting of the University of Edinburgh A condition was considered active if the participant had experienced symptoms in the preceding six months. The most common active co-occurring condition was irritable bowel syndrome, with clinical depression, fibromyalgia, anaemia and hypothyroidism also featuring prominently. Women also reported, on average, more symptoms than men – 42 compared with 36. The most common of these symptoms were brain fog – a term commonly used to describe the cognitive impairment experienced by participants – unrefreshing sleep and muscle pain. These findings highlight the very serious impact ME/CFS has on women who are disproportionately affected Sonya Chowdhury, chief executive of Action for M.E Participants were also asked to define the severity of their illness from mild to very severe using definitions from the UK’s National Institute for Health and Care Excellence guidelines. Experts identified that being a woman and having ME/CFS for more than 10 years are risk factors for severe illness, with symptoms increasing in intensity as they age. Professor Chris Ponting, study lead from the MRC human genetics unit at the University of Edinburgh’s Institute of Genetics and Cancer, said: “ME/CFS is a devastating disease affecting a UK population the size of Derby. “We discovered that the disease is worse for women, in older people, and many years after their ME/CFS started. “Our hope is that DecodeME’s genetic results will shed light on why certain groups are more susceptible to ME/CFS than others.” Sonya Chowdhury, chief executive of Action for M.E. and chair of the management group of the study, said: “These findings highlight the very serious impact ME/CFS has on women who are disproportionately affected. “It’s important to also recognise the impact that it has on men who have ME/CFS and we thank the 20,000 men and women who have already signed up to take part in this very important study. “We still need more to join us, so if you are 16 or older, live in the UK and have a diagnosis of ME/CFS, please do take part now to help us decode ME at www.decodeme.org.uk/portal.” Read More Charity boss speaks out over ‘traumatic’ encounter with royal aide Ukraine war’s heaviest fight rages in east - follow live 4 hacks to get teens off the sofa and get active – as study warns of heart damage Taking adult education classes may lower risk of dementia, study suggests Indiyah Polack: I didn’t want to go on Love Island because of my acne

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While women have long complained about the negatives of menopause, Kelly Ripa has recently discovered one benefit of going through the process. In a recent episode of her podcast, Let’s Talk Off Camera With Kelly Ripa, the Live With Kelly and Mark host discussed an under-appreciated aspect of menopause that she recently experienced herself. “I love not getting my period,” Ripa, 53, told her podcast guest and her real-life hormone doctor, Dr Erika Schwartz. The TV personality said that she experienced the beginning of menopause during the Covid-19 pandemic. Menopause, according to the Mayo Clinic, marks the time in a person’s life when their menstrual cycle ends and they no longer get their period. However, Ripa recalled the moment she learned of a main upside to menopause - the ability to wear white pants without fear of getting her period. “My first Memorial Day through Labor Day after menopause… it was the summer of the white pants because I never had to worry about wearing white pants,” Ripa recalled. The All My Children alum went on to speak with Dr Schwartz about the misconceptions of menopause, and how many people still consider the topic to be taboo. “People still whisper the word menopause,” she said, adding that “the information is still so hidden”. Her hormone doctor agreed, noting that “we’re still in the Dark Ages” when it comes to menopause and described the process as “like a bad secret”. Ripa said that even her friends of the same age are in denial going through menopause. She revealed that some of her friends routinely “tell me they still get their periods regularly”, while others consider the process to be “embarrassing”. “They’re talking to me, an open book, and still cannot bring themselves to talk about having gone through menopause. It is too scary for them to acknowledge,” she said. Dr Schwartz maintained that some women have trouble opening up about menopause because they feel it’s a sign that they’re “no longer useful” in society. “Because, in this day and age, there’s still a lot from yesterday’s day and age that has permeated the society and culture,” the doctor said. “And we think that being aged beyond menopause, we’re no longer useful.” “The moment you’re no longer fertile, you’re not useful,” Dr Schwartz continued. “I think you’re very useful. That’s when you have the information, the experience. You have so much to bring to the table, that I think every woman should feel great about herself.” Ripa has been married to husband Mark Consuelos since 1996. The longtime couple share children Michael, 26, Lola, 22, and Joaquin, 20. The TV host previously revealed that when she first started going through menopause, she mistakenly thought that she was pregnant. Speaking to Haute Living about her book, Live Wire: Long-Winded Short Stories, in 2022, she recalled the moment she believed her husband had accidentally “got [her] pregnant”. “I started taking pregnancy tests daily, but then Mark sort of gingerly said: ‘Could there be another reason why you’re not getting your period?’ and me saying: ‘What other reason could there possibly be?’ He really had to walk on eggshells here [by explaining to me that I was probably going through menopause],” Ripa said. However, she ultimately felt relieved that she wasn’t pregnant. “I was really grateful that I was not going to have to explain to my kids that they were about to meet their new sibling,” she joked. Read More Kelly Ripa says she thought she was pregnant when she first started going through menopause Viewers applaud Kelly Ripa and husband Mark Consuelos’s ‘great chemistry’ after Live co-hosting debut Kelly Ripa says she worked out of a janitor’s closet for years before ABC gave her a permanent office Teenager received a ‘zero’ at school because he didn’t have class supplies As transphobic hate crimes rise by 11% in a year, how to be a better ally All the big-ticket celebrity donations to Selena Gomez’s Rare Impact Fund Benefit

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