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Jonnie Irwin has spoken out about his “really good” experience with palliative care in a hospice, amid his journey with terminal cancer. The A Place In The Sun presenter, 49, appeared on BBC Morning Live on Monday (24 July) and gave viewers an update on his current health and treatment. Reassuring hosts Gethin Jones and Helen Skelton that his family is doing “great and very noisy”, Irwin was asked about his experience with palliative care, which focuses on improving the quality of life for anyone facing a life-threatening condition. Irwin said that he has been in palliative care since the day he received his terminal cancer diagnosis. He was first diagnosed with lung cancer in August 2020, but only publicly shared the news in November 2022 after it spread to his brain. He described his hospice experience as a “delight”, adding that his initial perception of such facilities were that they were “very much a boiling hot room full of people who looked frail and towards the end of their days”. However, it was “nothing of the sort” when he did actually go in. “It’s spacious, energised, comfortable,” Irwin told the show, adding: “I’ve had a really, really good experience at my hospice.” He urged anyone who is facing a terminal diagnosis to “embrace” end-of-life care and to try going to a hospice if they have been offered the choice. “My first experience of palliative care and hospice was blood transfusions,” he explained. “I had my first blood transfusion in hospital and then was invited to use the hospice, so I have it a go as a day patient and went into a lovely room. “I implore people to check out hospices. If you’ve got the choice of using it, then use it… I encourage people to explore that option because it’s not the doom and gloom operation you might think it was.” In June, Irwin made a rare red carpet appearance at the Television and Radio Industries Club (TRIC) Awards and said he is taking “every day as a gift as it comes”. When he first revealed his terminal cancer diagnosis, the Escape To The Country host said he “doesn’t know how long” he has left to live, but hopes he will inspire people to “make the most of every day”. He also celebrated his “best ever” Father’s Day last month with his three sons, Rex, four, and twins Rafa and Cormac, three, with wife Jessica Holmes. Irwin recently revealed that sometimes he has to “remove himself” from his family home to go to a hospice when he is in a lot of pain because it makes him “not good to be around”. He told Hello! magazine: “I’m like a bear with a sore head and I don’t want [my family] to be around that.” In another appearance with podcast OneChat previously, he said that being in pain affects his mood, explaining: “I have been close to death’s door, twice at least. You lose your memory, you lose your patience. I have got a very short temper. It’s not made me a better person, that’s for sure.” Read More Ruth Handler: The Barbie inventor who revolutionalised prosthetic breasts and narrowly avoided prison Fans defend Prince Harry and Meghan Markle amid breakup rumours Tim Shaddock rescue: Ben Fogle offers to pay for Australian sailor and dog to be reunited after emotional separation Carol Vorderman shares warning to sunbathers after skin cancer scare This is how often you should actually change your razor Are we working out too hard?

Max Verstappen will not start Sunday’s Belgian Grand Prix from pole position with the world champion set to serve a five-place grid penalty. Verstappen, 110 points clear at the top of the standings, is due to take on his fifth gearbox, one more than he is permitted. It means the 25-year-old will begin the grand prix on Sunday no higher than sixth in something of a boost to his forlorn rivals. However, the Dutchman started the race from 14th last year owing to engine penalties and still took the win in his dominant Red Bull machine. Verstappen has won the last seven races, nine of the 11 rounds staged so far this season, and is on course to wrap up a hat-trick of titles. At last weekend’s Hungarian Grand Prix, Verstappen’s Red Bull team set a new F1 record of 12 consecutive wins. Qualifying for Sunday’s race is due to take place at 5pm local time (4pm BST) on Friday. A sprint race will be staged at Spa-Francorchamps on Saturday, but Verstappen’s penalty will apply only to the main event. Read More Charity boss speaks out over ‘traumatic’ encounter with royal aide Ukraine war’s heaviest fight rages in east - follow live

Liam Payne is on the road to recovery, as he revealed that he was recently hospitalised due to a kidney infection. The singer, 29, took to Instagram on 25 August to share the news, while he announced that his upcoming tour - which was supposed to start next month - is going to be postponed. He expressed that his doctors advised him to focus on his health, after he’d been hospitalised due to a kidney infection. “It’s with a heavy heart I have to tell you that we have no other choice but to postpone my upcoming tour of South America,” he wrote in the caption, alongside a video of himself. “Over the past week I’ve been in hospital with a serious kidney infection. It’s something I wouldn’t wish on anyone, and doctors orders are that I now need to rest and recover.” While Payne expressed that he was “beyond excited to play” music, he acknowledged that fans will soon be refunded for their tickets. However, the former One Direction member also added that the new dates haven’t been decided yet. “To all of you who have bought tickets, I’m so sorry. We’re working to reschedule the tour as soon as we possibly can, but for now we will be refunding the tickets. So, please look out for updates from your point of purchase,” he wrote. “Thanks as always for the love and support, and look forward to seeing you soon.” In his video, the “Bedroom Floor” singer went on to describe how he’d been a “bit unwell” recently, following the “bad kidney infection”. “We started rehearsals, and I’ve just been advised that now is not the right time for me to be out on the road, trying to recover from this,” Payne said. “I have the best people around me at home trying to help me recover as we speak.” He also added that he hopes that when the time comes, he could “put on an even bigger show” for his fans. According to the National Health Service, hospitalisation as a result of kidney infection can occur for a variety of reasons - such as when a patient is severely dehydrated, unable to swallow or keep down any fluids or medicines, or has a weakened immune system. Fans rushed to the comments section of Payne’s video, where they sent him sweet messages and hoped for him to make a healthy recovery. “Always got your back, champ,” one wrote, while another added: “Get well soon! Love you and here for you forever and always.” A third wrote: “Sending one massive BIG hug your way.” The tour was initially set to kick off on 1 September in Lima, Peru, with his final show in Mexico City, Mexico, on 12 September. In July, Payne made his official return to his YouTube channel, where he discussed how excited he was to go back on tour. He also spoke candidly about his health, after finishing a 100-day rehabilitation stay and was nearly six months sober. Payne went on to admit that prior to sharing the YouTube video, he removed himself from the public eye for his mental well-being. “I just needed to take a little bit of time out for myself actually, because I kind of became somebody who I didn’t really recognise anymore,” he explained. “And I’m sure you guys didn’t either. I was in bad shape up until that point and I was really happy to kind of put a stopper to life and work.” In the YouTube video, the “Strip That Down” singer also discussed his appearance on Logan Paul’s podcast, Impaulsive. Payne expressed regret for some of the things he said about Zayn Malik, after professing that there were “many reasons why he disliked” his former One Direction bandmate. “I think for me, a lot of what I said just came from the wrong place,” Payne recalled. “I was so angry at what was going on around me that instead of taking a look inwards I decided to take it outwards.” Payne said he thought his anger stemmed from frustrations with his career and, rather than reflecting privately, he took his feelings out on others. He added that he “wanted to apologise” for his behaviour. Read More Liam Payne apologises for Zayn Malik comments as he completes 100 days in rehab Zayn Malik discloses ‘underlying issues’ that led to him quitting One Direction: ‘We got sick of each other’ Liam Payne says he’s over 100 days sober: ‘I feel amazing’ ‘Boy moms’ receive backlash for teaching sons how to cook - but for the wrong reason This is how stress affects different parts of the body Chris Pratt’s daughters give him a glittery makeover

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Sergio Perez will be eyeing a dream victory on home soil at the Mexico City Grand Prix this weekend. The Red Bull driver has endured a difficult few months and has not won since Azerbaijan in April. His team-mate Max Verstappen, however, has won 15 races this season and has already sealed his third world title. Verstappen was triumphant last week at the US Grand Prix in Austin where Lewis Hamilton - who finished second - was disqualified alongside Charles Leclerc for an illegal floor. Lando Norris came home third, but was promoted to second after Hamilton’s DSQ, for his 12th podium in F1 but the McLaren driver is still chasing his first win. Verstappen won last year’s race at the Autodromo Hermanos Rodriguez. Here is everything you need to know. What is the race schedule? (All times BST/GMT) Friday 27 October Free practice 1: 7:30pm Free practice 2: 11pm Saturday 28 October Free practice 3: 6:30pm Qualifying: 10pm Sunday 29 October Race: 8pm How can I watch it online and on TV? The entire race schedule from Mexico will be broadcast live on Sky Sports F1 and Sky Sports Main Event in the UK and Ireland. Sky’s coverage of the race on Sunday starts at 6:30pm (GMT). The weekend’s action will be broadcast on ESPN in the United States. Free-to-air highlights in the UK will be aired on Channel 4; for qualifying at 8:30am (GMT) on Sunday morning and the grand prix early on Monday morning at 1am. Sky Sports subscribers can watch all the action in Mexico on the Sky Go app. If you’re not a Sky customer you can grab a NOWTV Day Pass here to watch without a subscription. Driver Standings 1) Max Verstappen - 466 points (champion) 2) Sergio Perez - 240 points 3) Lewis Hamilton - 201 points 4) Fernando Alonso - 183 points 5) Carlos Sainz - 171 points 6) Lando Norris - 159 points 7) Charles Leclerc - 151 points 8) George Russell - 143 points 9) Oscar Piastri - 83 points 10) Pierre Gasly - 56 points 11) Lance Stroll - 53 points 12) Esteban Ocon - 44 points 13) Alex Albon - 25 points 14) Valtteri Bottas - 10 points 15) Nico Hulkenberg - 9 points 16) Yuki Tsunoda - 8 points 17) Zhou Guanyu - 6 points 18) Kevin Magnussen - 3 points 19) Liam Lawson - 2 points 20) Logan Sargeant - 1 point 21) Nyck de Vries - 0 points 22) Daniel Ricciardo - 0 points Constructors’ Championship 1) Red Bull - 706 points (champions) 2) Mercedes - 344 points 3) Ferrari - 322 points 4) McLaren - 242 points 5) Aston Martin - 236 points 6) Alpine - 100 points 7) Williams - 26 points 8) Alfa Romeo - 16 points 9) Haas - 12 points 10) AlphaTauri - 10 points What is the 2023 F1 calendar? ROUND 20 - MEXICO Autodromo Hermanos Rodriguez, Mexico City - 27-29 October ROUND 21 - BRAZIL (sprint weekend) Interlagos Circuit, Sao Paulo - 3-5 November ROUND 22 - LAS VEGAS Las Vegas Street Circuit - 16-18 November ROUND 23 - ABU DHABI Yas Marina Circuit - 24-26 November Read More Red Bull hire bodyguards for Max Verstappen over safety concerns at Mexico GP Willy T Ribbs: ‘There were death threats – but I was never going to play the victim’ Mercedes chief admits ‘embarrassment’ after Lewis Hamilton disqualification Nicolas Hamilton: ‘Lewis has never put a penny into my racing... it’s not easy being related to him’ Zhou Guanyu interview: ‘There is a lot of pressure in F1 – only winners stay in this sport’ Daniel Ricciardo is back - and this time he wants to go out on top

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Researchers have revealed how muscle cells deteriorate with age, affecting their ability to regenerate and recover after an injury. The findings could help to shed light on why it takes people longer to recover from muscle damage as they age. A team at Nottingham Trent University analysed the genes inside muscle cells, and found the ‘development pathways’ – the different ways in which genes work together to regenerate muscle – become weakened in older cells. We know that healthy muscle regenerates after we’ve had an injury but ageing impairs that regeneration potential and recovery gets harder the older we get Dr Livia Santos, Nottingham Trent University Lead researcher Dr Livia Santos, an expert in musculoskeletal biology in Nottingham Trent University’s School of Science and Technology, said: “This goes some way towards explaining why muscle injuries may take longer to recover as we get older.” She added: “We know that healthy muscle regenerates after we’ve had an injury but ageing impairs that regeneration potential and recovery gets harder the older we get. “What we’ve observed, in terms of what happens inside the cells, helps us to better understand why we don’t heal as well or as quickly in older age. “The pathways that control cell processes and development work differently in older cells and are downregulated, meaning regeneration is impacted the older we get. “If we can understand these pathways, however, we could potentially identify new therapies and interventions to mitigate the problem.” The researchers developed a new approach to examine muscle cells in the laboratory to enable them to observe the different mechanisms that drive muscle ageing. They studied muscle cells from donors, chemically injuring cells after they had been donated and isolated, then assessing how they heal and regenerate back to their pre-injury baseline levels. When they looked at cells from a 20-year-old and a 68-year-old donor, researchers found distinct differences in the development pathways of the younger and older cells. While younger muscle cells fully recovered from the injury, the team found that in older cells the genes expressed less of what they needed to, leaving the cells no longer able to perform in the way they should. According to the researchers, this contributes to reduced regeneration capacity leading to thinner, less robust ‘myotubes’ – a type of cell that can fully develop into a muscle fibre. Muscle regeneration is a complex and finely balanced biological process and is known to deteriorate with ageing, leading to the decline of musculoskeletal health and in some cases metabolic and genetic diseases. Our work enables us to examine muscle cell regeneration across the lifespan and this in turn could be key for future drug discovery for disease related to muscle ageing Researcher Janelle Tarum Janelle Tarum, another researcher on the study, said: “We’ve been able to develop a new approach to assess muscle regeneration which involves a state-of-the-art technique called RNA-sequencing. “There’s a very clear reduced regeneration capacity and weakened recovery of aged cells and we have been able to further understand the factors underlying this impairment. “Our work enables us to examine muscle cell regeneration across the lifespan and this in turn could be key for future drug discovery for disease related to muscle ageing.” The study, which also involved Manchester Metropolitan University and Liverpool John Moores University, is published in the Journal of Tissue Engineering and Regenerative Medicine.

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