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Trends come and go, but if you had to bet all your chips on one colour never going out of fashion, you can bank on black. And as designers ditch colour in their collections and crave the fluid, liquid lines of fashion’s darkest and most addictive shade, you can embrace mood-boosting monochrome and jet black without any fear of making a fashion faux pas – or bad buy. From a showy shoulder at Balmain – who would have thought that a PVC maxi dress could look even more sultry? …To sexy, slinky sequins at Michael Kors; tailored, long black coats (LBC) at Max Mara, Dolce & Gabbana, Victoria Beckham and Prada, black is more than a shot in the dark this season – and the devil is in the detail. To get the catwalk look, here’s what’s hot on the high street and will make a great first impression… Black blazer Call it the power blazer, Le Smoking, or straightforward tailored trouser suit, this is your wardrobe staple to look sharp. “The trouser suit is an icon of sophistication and confidence,” says Zoe de Abreu, co-founder of Ro&Zo. “A black blazer matched with trousers will be the perfect companion for all occasions, as it transcends perfectly from day to night.” For a dare-to-bare aesthetic, go topless underneath – apart from a sexy black bralette – and accessorise with a cosmic choker or pukka set of pearls. Ro&Zo Black Belted Blazer, £129; Black Pleat Detail Trousers, £109. Reiss Alia Slim Fit Single Breasted Satin Suit Blazer, £268; Alia Flared Satin Waistband Suit Trousers, £178. Showy shoulder “The off-shoulder trend takes on a new dimension this autumn, adding a feminine touch to seasonal wardrobes,” opines de Abreu. She says this trend is elegant and feminine, and can be worn in a range of textures, such as jersey, velvet and Merino wool. Moreover, baring a shoulder is very flattering – the neckline lengthens the neck, frames the face – and is a great transitional, versatile piece with a good measure of va-va-voom. Ro&Zo Black Jersey One Shoulder Top, £49; Ombre Sequin Skirt, £129. Reiss Adele Velvet Off-The-Shoulder Jumpsuit, £178. Luxe lace Ladylike lace has been reimagined with trims adorning jersey and velvet – and it’s made a beeline for the little black dress. Whether a flattering midi dress is crafted from a luxuriously soft jersey that contours your curves, “A delicate lace-tiered hem adds a dramatic finishing touch,” says Karen Peacock, chief creative officer and co-founder, Albaray. Or embellished on the neckline and hemline of velvet, sheer lace channels some vintage charm with the X-factor. In fact, if you’re feeling thrifty, be inspired by ribbon and trim shops and think about sewing a lace trim on an existing black dress for an instant update. Albaray Jersey & Lace Mix Dress, £89. LK Bennett Anouk Black Velvet And Lace Dress, £429. Sparkle Whether you go full-out sequins or dazzle in rhinestones, a sexy shimmer is where it’s at. “For autumn, sequins really capture the essence of festivity, allure and drama,” notes de Abreu. “Sequins are all about adding a touch of glamour to your look, and letting your outfit take the centre stage.” Moreover, “A flattering silhouette is created with a sequin halter top and matching flared trousers,” says Peacock. “Wear together to make a statement, or dress down and style with jeans or a simple T-shirt,” she adds. Next Flutter Sleeve Tie Waist Mini Dress, £60. Albaray Sequin Top, £69; Sequin Trousers, £99 – available mid-October. Long black coat A long black coat may not set your pulse racing, but the LBC took to the runway in its droves, with designers making it a key piece in their collections. And let’s face it, nothing looks more elegant or grown-up than wrapping yourself in wool. Just make sure it’s calf-length or longer. As Peacock puts it: “A sharply tailored black coat is a true investment piece, which is both functional and stylish.” “With the ability to style casually or formally, it will be a go-to during the colder months for years to come.” Next Belted Long Coat, Black, £62. John Lewis Hand Finished Robe Belt Wool Blend Coat Black, £159; other items from a selection Read More How to prep your home for when the clocks go back Menopause campaigner Mariella Frostrup: ‘I look forward to a future where women gradually stop feeling so ashamed’ More girls miss school and college due to their periods than colds, survey finds More girls miss school and college due to their periods than colds, survey finds How to look after your immune system as the weather changes How to protect your plants as the first frosts arrive

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The combination here tastes wonderful whether you’re using fresh raspberries in season (when they’re cheaper) or frozen raspberries,” says former Great British Bake Off contestant Hermine Dossou. “To enhance the flavour of your desiccated coconut, you could toast it lightly (for five minutes or so) while preheating the oven – but keep an eye on it as it does turn brown very quickly.” Coconut, raspberry and chocolate muffins Makes: 12 Ingredients: 180g milk 2 large eggs 60g vegetable oil 60g unsalted butter, melted 230g sugar 1 tsp vanilla extract ½ tsp ground cinnamon ½ tsp ground nutmeg 5g salt 250g plain (all-purpose) flour (gf plus ½ tsp xanthan gum) 80g desiccated (dried shredded) coconut 10g baking powder (gf) 150g raspberries 150g milk chocolate, chopped into chunks Method: 1. Preheat the oven to 200C/180C fan/400F/gas 6 and line a 12-hole muffin tin with paper cases. 2. In a large mixing bowl, mix together the milk, eggs, oil, butter, sugar, vanilla, cinnamon, nutmeg and salt for about a minute, until well combined. Add the flour, coconut and baking powder and stir until fully incorporated. Fold in half the raspberries and all the chocolate chunks. 3. Divide the batter equally between the muffin cases. Top each muffin with a couple of the remaining raspberries. Bake for 25–30 minutes, or until the muffins have risen and are golden brown. You can keep these for a few days in an airtight container, or, once cooled, freeze them for up to 3 months. They are lovely served warm – either out the oven or reheated for a few seconds in the microwave. ‘The Thrifty Baker’ by Hermine Dossou (White Lion, £18.99).

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Alcohol addiction ruins millions of lives every year, but scientists may have found a cure for this terrible affliction. A new treatment for alcohol use disorder (AUD) has been trialled in monkeys with impressive results and, if these translate to human trials, the impact could be monumental. A team of neuroscientists and physiologists from across the US tested a new type of gene therapy to see if they could directly target the underlying brain circuitry associated with sustained heavy drinking. As they noted, in the journal Nature Medicine, people suffering from AUD commonly return to alcohol use even if they attempt to quit. This is largely to do with what’s known as mesolimbic dopamine (DA) signalling – meaning how the central nervous system circuit communicates the feelgood neurotransmitter dopamine. A protein called glial-derived neurotrophic factor (GDNF) is key to keeping these neurons in this reward circuitry functioning. However, experts have found that levels of GDNF are reduced in people with AUD during periods of alcohol abstinence, most notably in a region of the brain called the ventral tegmental area (VTA), as IFLScience notes. Therefore, the researchers decided to test whether using gene therapy to deliver more GDNF to the VTA could help reinforce this crucial dopaminergic signalling and prevent patients from suffering an alcoholic relapse. The team of scientists explained how alcohol consumption in non-addicts prompts the release of dopamine, creating a pleasurable buzz feeling, but chronic alcohol use causes the brain to adapt and stop releasing so much dopamine. “So when people are addicted to alcohol, they don’t really feel more pleasure in drinking,” Dr Kathleen Grant, a senior co-author of the study, said in a statement. “It seems that they’re drinking more because they feel a need to maintain an intoxicated state.” For their research, Dr Grant and her colleagues used eight rhesus macaque monkeys, who were exposed to increasing concentrations of alcohol over four 30-day “induction” periods. The monkeys then had free access to alcohol and water for 21 hours a day for six months, during which they developed heavy drinking behaviours. This was then followed by a 12-week abstinence phase, with the GDNF treatment performed four weeks in for half of the subjects. The gene therapy was delivered using a a viral vector containing a copy of the human GDNF gene injected directly into the primate’s VTA, according to IFLScience. And the results were truly jaw-dropping. “Drinking went down to almost zero,” Dr Grant said. “For months on end, these animals would choose to drink water and just avoid drinking alcohol altogether. They decreased their drinking to the point that it was so low we didn’t record a blood-alcohol level.” The most exciting aspect of their findings is the suggestion that gene therapy could offer a permanent solution for people with the most severe cases of AUD. This will be a welcome glimmer of hope to many, given that some 29.5 million people were diagnosed with AUD in the US alone in 2021, according to the National Institute on Alcohol Abuse and Alcoholism. Of these 29.5 million sufferers, almost a million (894,000) were aged between 12 and 17. It’ll likely be some time before we know for sure whether the gene therapy can be rolled out in humans, but it’s an important first step in tackling this devastating disorder. Sign up for our free Indy100 weekly newsletter Have your say in our news democracy. Click the upvote icon at the top of the page to help raise this article through the indy100 rankings.