For disorganized people who prefer to fly by the seat of their pants, backpacks are the no-brainer choice when it comes to travel bags that won't weigh them down. The travel backpack, at best, offers the capacity to streamline up to up to one week's worth of clothing; at worst, it's a sad sack that leaves its contents more jumbled than when it was first stuffed in. If you're looking to avoid the latter situation, it's best to buy a backpack that's already designed to organize your travel essentials for you.

Harry Styles is the latest celebrity to be replicated in wax form as Madame Tussauds has unveiled not one, but seven wax figures of the popstar after receiving "thousands of fan requests." The seven waxworks will be on display at museums in London, New York, Los Angeles, Amsterdam, Berlin, Singapore and Sydney, each of them sporting some of the singer's iconic looks from recent years. In London, the Harry figure wears a double-breasted hunter green blazer, large flower broach, pistachio green trousers, ivory boots and a bright green handbag, the look is paired with a classic pearl necklace jewellery which references Styles's My Policeman premiere outfit during the 2022 Toronto International Film Festival. Sign up to our free Indy100 weekly newsletter After it took 10 months for Madame Tussauds’ artists to complete, the public can see the figure for themselves when it premieres on July 27. In New York, the Harry waxwork will sport the memorable sequin rainbow jumpsuit wore during his 2022 headlining Coachella set, while Berlin's figure will wear Styles's another of his Coachella costumes - an oversize faux fur coat paired with a metallic leather waistcoat and trousers. While some of the other figures will don outfits the As It Was singer has previously worn during his Love On Tour concert series. Sydney’s Styles figure dons a pink satin shirt, burgundy trousers and a feather boa, from one of his shows in San Jose, California. A bronze sequin vest with fringe attached originally worn at a gig in Long Island, New York, is what the LA wax figure will have on, while in Amsterdam it will be a a pink double-breasted suit with floral embroidery, similar to a look he wore on stage in Dallas. For Singapore's Styles waxwork, a blue and yellow two-piece from the Glasgow leg of his Love On Tour concert series will be sported. But what do Harry fans make of the waxwork - here are some of the best reactions to the Harry Styles London waxwork: Many were impressed with the images they saw of the figure, describing it as "scary accurate." Though others disagreed, and while they note it isn't the worst waxwork they've seen, they noted how "something is off." While others made some comparisons, from Margaret Thatcher to Princess Diana, Benedict Cumberbatch and Don't Worry Darling co-star Chris Pine... Fans can see the Harry Styles waxwork in person at Madame Tussauds in London from July 27. Have your say in our news democracy. Click the upvote icon at the top of the page to help raise this article through the indy100 rankings.

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Women who smoke during pregnancy are 2.6 times more likely to give birth prematurely compared with non-smokers – more than double the previous estimate, new research suggests. The University of Cambridge study also found smoking meant the baby was four times more likely to be small for its gestational age, putting it at risk of potentially serious complications including breathing difficulties and infections. There was no evidence caffeine intake was linked to negative outcomes. We’ve known for a long time that smoking during pregnancy is not good for the baby, but our study shows that it’s potentially much worse than previously thought Professor Gordon Smith, University of Cambridge Professor Gordon Smith, head of the department of obstetrics and gynaecology at the University of Cambridge, said: “We’ve known for a long time that smoking during pregnancy is not good for the baby, but our study shows that it’s potentially much worse than previously thought. “It puts the baby at risk of potentially serious complications from growing too slowly in the womb or from being born too soon. “We hope this knowledge will help encourage pregnant mums and women planning pregnancy to access smoking-cessation services. “Pregnancy is a key time when women quit and if they can remain tobacco free after the birth there are lifelong benefits for them and their child.” The NHS recommends that women who are pregnant should stop smoking and limit their caffeine intake because of the risk of complications to the baby. When the toxins from smoke travel through the bloodstream to the baby, it struggles for oxygen. When this happens it affects their development, and is linked to premature birth and low birthweight, though it has also been linked to a reduced risk of pre-eclampsia (high blood pressure during pregnancy). High caffeine intake has also been linked to lower birthweight and possibly foetal growth restriction. But caffeine can be more difficult to avoid than cigarette smoke as, as well as being found in coffee and tea, it can be found in chocolate, energy drinks, soft drinks and certain medications. Researchers say studies looking at the links between smoking and caffeine and their impact on pregnancy tend to rely on people reporting how much they have consumed, or exposure to smoke, data which is not always reliable. Blood tests for metabolites – chemical by-products created when substances such as tobacco and caffeine are processed in the body – might be more accurate. Researchers at Cambridge and the Rosie Hospital, part of Cambridge University Hospitals NHS Foundation Trust, recruited more than 4,200 women who attended the hospital between 2008 and 2012 as part of the Pregnancy Outcome Prediction (POP) study. The team analysed blood samples taken from a group of these women four times during their pregnancies. To assess exposure to cigarette smoke, the team looked at levels of cotinine, which can be detected in blood, urine and saliva. Only two out of three women with detectable levels of cotinine in every blood sample were self-reported smokers, showing that this measure is a more objective way of assessing smoking behaviour, researchers say. A total of 914 women were included in the smoking analysis. Of these, 78.6% were classified as having no exposure to smoking while pregnant, 11.7% as having some exposure and 9.7% as having consistent exposure. The study, published in the International Journal of Epidemiology, found that compared with those without smoke exposure while pregnant, those with consistent exposure were 2.6 times more likely to experience spontaneous preterm birth. According to the researchers, this is more than double the previous estimate of 1.27 from an analysis of multiple studies. They were also 4.1 times as likely to experience foetal growth restriction. Additionally, babies born to smokers were found to be on average 387g lighter than babies born to non-smokers – that is, more than 10% smaller than the weight of an average newborn. This increases the risk that the baby will have a low birth weight (2.5kg or less), which in turn is linked to an increased risk of developmental problems as well as poorer health in later life. Unlike in previous studies, the team found no evidence that smoking reduced the risk of pre-eclampsia. To assess caffeine intake, researchers looked for the metabolite paraxanthine in 915 women. Of these women, 12.8% had low levels of paraxanthine throughout pregnancy (suggesting low caffeine intake), 74.0% had moderate levels and 13.2% had high levels. The researchers say there was little evidence of an association between caffeine intake and any of the negative outcomes. However, because the researchers did not study all possible adverse outcomes of pregnancy, and some of the outcomes not studied – such as stillbirth – have been associated with higher caffeine intake in previous studies, they cannot interpret the findings as indicating that current recommendations around caffeine intake should be changed. The work was supported by the National Institute for Health and Care Research (NIHR), Cambridge Biomedical Research Centre and the Medical Research Council. 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