PARIS French spirits group Remy Cointreau on Tuesday reported a well-flagged 35% fall in first quarter organic sales,

Oti Mabuse has revealed that she and her husband Marius Iepure had stopped trying to conceive when she discovered she is pregnant with their first child. The former Strictly Come Dancing star announced on Saturday (26 August) that she is expecting, describing the pregnancy as “the best news we could have ever asked for”. Mabuse, 33, shared in an Instagram Story on Monday (28 August) that she had initially “given up” on trying to conceive because “nothing was happening”. She posted a video of her and her friend Nkateko Dinwiddy celebrating her pregnancy, and wrote over the clip: “My friend @takkies7 asked me to [take a pregnancy test] because I was drinking coffee and I don’t drink coffee. “We had been trying for a while and decided to stop (it all just got too much) and just live life as us two as nothing was happening. “We enjoyed each other’s company, dinners, concerts, parties, just simply removed all the pressure and here we are!” In another Instagram Story, she shared a screenshot of a WhatsApp conversation between her and Dinwiddy, showing her friend asking if she had taken a pregnancy test yet. Mabuse replied: “Ahhhh why? [cry-laugh emoji] Don’t stress me I’ve actually given up.” But the Dancing On Ice judge shared the happy news over the weekend live on her ITV Breakfast Show. She also shared a series of photographs of her and Iepure cradling her growing baby bump on Instagram and wrote in the caption: “We love our little bundle of joy so much already… and can’t wait to see what our future will look like now as a family of three plus Leo. “It’s been a beautiful journey so far with close friends and family and nearly over but we have learnt a lot along the way… Christmas is about to get even louder.” Mabuse also shared a video montage of the moment the couple shared the news with their close friends and family over FaceTime and in person, including with her sister, Strictly judge Motsi Mabuse. The expectant mum said in her caption: “Living in a different country as a couple means you don’t have family around to break the news face to face to. “And most often, friends become family. We are so extremely lucky with our group of friends. Disclaimer: This isn’t all of them, not enough video space. But we kept our circle really tight, full of positive energy, laughter and joy.” Motsi left a comment under the video and said: “Just cried again [red heart emoji].” Mabuse and Iepure met in Germany as dance partners in 2012. He proposed to her in 2014 on her birthday and they married that same year. Read More ‘My depression ate me up and stopped me doing the thing in life I loved the most – cooking’ BBC Breakfast’s Emma Vardy announces birth of son: ‘Presenting my best breaking news ever’ Maya Jama and Stormzy ‘confirm relationship’ as they’re seen holding hands in Greece Oti Mabuse announces she is pregnant with her first child Amy Dowden reveals ‘life-threatening’ sepsis diagnosis amid cancer treatment BBC Breakfast’s Emma Vardy announces birth of first child

Continuing to untangle itself from the legacy of Covid, Cathay Pacific Airways Ltd. offered its junior pilots the

They Cloned Tyrone stars John Boyega and Teyonah Parrris play Choose Your Squad and reveal

Surgeons worked all day and into the night to ensure Britain’s first womb transplant went smoothly. Its success is down to meticulous research, years of sharing knowledge between experts around the globe, and the hard work and dedication of doctors Professor Richard Smith, from Imperial College London, and Isabel Quiroga, from the Oxford Transplant Centre. Around 50 babies have been born worldwide as a result of womb transplants, which give women missing a functioning uterus a chance to have a baby. In the first UK case, the operation to remove the womb from the recipient’s 40-year-old sister lasted eight hours and 12 minutes, with surgeons leaving her ovaries behind to prevent pushing her into early menopause. One hour earlier, surgeons began operating on the 34-year-old recipient, preparing her body to receive the donated organ. This operation lasted nine hours and 20 minutes, with the surgical team experiencing some difficulties including a higher-than-expected blood loss of two litres. However, after just 10 days, the recipient was well enough to leave the hospital and has continued to have a good recovery. She is also having regular periods, which shows the womb is working well. Her sister was discharged five days after her donor operation and has also made a good recovery. Removing a womb is a similar operation to a radical hysterectomy, according to Prof Smith, who as well as being a gynaecological surgeon is the clinical lead at the charity Womb Transplant UK. He and Miss Quiroga led the team of more than 30 staff who worked on the transplant one Sunday in February. Prof Smith and Miss Quiroga removed the older sister’s womb, cervix and fallopian tubes, plus crucial blood vessels around the organ. The main vessels are the uterine arteries running into the womb, but the surgeons also aimed to collect some of the larger internal vessels that lead into the smaller branch of the womb. Prof Smith said surgeons doing these operations have to retrieve veins involved in the drainage of the womb. “One of the amazing things is that my surgical skill-mix as a cancer surgeon is to remove organs with a margin of normal tissue, while sealing the vessels as I go,” he said. “Transplant surgical skills are different – that is to remove a normal organ with the best number of non-sealed vessels as you can. “Isabel and I operate together with no ego – it just flows backwards and forwards across the table.” He added: “The day itself was truly humbling. We turned up at 7am at the Churchill transplant centre with the donor and the recipient families, then we went into a pre-op huddle. Those in the huddle included surgeons, nurses, anaesthetists and technicians. Prof Smith and Miss Quiroga worked to remove the womb, before the organ was prepared for transplantation by a “back table” team. “This was an organ which had a very, very unusual blood supply,” Prof Smith said. “In fact, it had a set of blood vessels which I’ve never seen in my entire career. They made my dissection a bit harder than it might have been, but we got there.” In the theatre next door, one hour before the retrieval of the womb was completed, surgeons began to operate on the donor’s younger sister to enable her to receive the womb. Prof Smith and Miss Quiroga switched from donor to recipient and Prof Smith removed the vestiges of the underdeveloped womb the recipient was born with. Meanwhile, the organ was packed and transported between the two theatres under sterile conditions to prevent contamination. A sterile bag with a cold perfusion solution contained the womb, which was then placed into a container with ice. During surgery, ligaments attached to the womb were attached to the recipient to help the womb stay in a relatively fixed place so it does not move around the pelvis. The most important part of the transplant operation was the joining of the very small vessels that give the blood supply to the womb. This was the most delicate and difficult part of the operation and was led by Miss Quiroga. Once all the vessels were connected, the donor’s vaginal cuff – around a 1cm part – was stitched into her sister’s vagina. If and when the recipient is able to complete her family, the womb will be removed six months later to prevent her from needing immunosuppressants for the rest of her life. Prof Smith said: “We know that the chance of failure at the point where the uterus goes in – if you look at the world literature – is 20 per cent to 25 per cent. And that failure is usually on the basis on sepsis and thrombosis. So technically, we are up to the job, but what happens thereafter can be scary. “Once you get to three or four days later, the chance of failure drops to probably less than 10 per cent. “Once you get to two weeks – and at the point where the woman has a period – the chance of her having a baby at that point is very high and the chance of failure has dropped to low. But those first two weeks – it’s very scary as a surgeon to watch and wait.” Biopsies to check the womb was functioning were read in London but then also confirmed by an expert team in the US at Baylor University Medical Centre in Dallas, where other womb transplants have been performed. Prof Smith said the procedure gives new hope to women born with devastating conditions. He said: “You’ve got girls, maybe 14, who have not had periods, they go to the GP and a scan shows there is no uterus. Absolute catastrophe. “Up until now, there’s been no solution for that, other than adoption or surrogacy... That’s not the case now. It’s really exciting.” On whether transgender women may also benefit from the operation, Prof Smith said that was still a long way off. He said the pelvic anatomy, vascular anatomy and shape of the pelvis are different, and there are microbiome issues to overcome. “My own sense is if there are transgender transplants that are going to take place, they are many years off. There are an awful lot of steps to go through. My suspicion is a minimum of 10 to 20 years.” Miss Quiroga said the living donor programme to date in the UK has focused on women with relatives who are willing to give their wombs. “It will come to a point where we will have friends or altruistic donors, like we have with many other transplants, but at the moment we’re only focused on people who have come forward with relatives,” she said. Read More Bursts of activity that make you huff and puff ‘linked to reduced cancer risk’ Fiona Phillips, 62, reveals she has Alzheimer’s disease Woman has all her teeth removed after rare vomiting condition causes them to fall out Bursts of activity that make you huff and puff ‘linked to reduced cancer risk’ Fiona Phillips, 62, reveals she has Alzheimer’s disease Woman has all her teeth removed after rare vomiting condition causes them to fall out

Vineyards and apple orchards across the Northeast are still gauging damage from a late-season frost in May that wiped out a third to most of the crop for some growers who say it's the worst frost damage they've ever seen

Take the Home Security, Cameras, and Smart Locks Survey (US Only) OFFICIAL SWEEPSTAKES RULES NO

Ted Lasso (Jason Sudeikis) always encourages his players to "be a goldfish" so they can

Super Sale Alert: Get 15% off sitewide (excluding subscriptions) at August with our promo code REFINERY15 now through August 20.

Going for a stroll in a park or market might seem to be a public

Air travelers have been putting up with widespread delays all month, and it's continuing again, as bad weather rakes the Northeast

SAVE 21%: As of June 8, the Amazon smart air quality monitor is on sale