With new research emerging, more questions have been raised about weight-loss injections, how they work, and the risks involved. Here are some of your questions answered. What are weight loss injections? Championed by some celebrities, including Elon Musk, weight loss injections were originally created to treat people with type 2 diabetes and other weight-related health issues. They are a type of prescription-based medical treatment that interferes with your metabolism, regulates your appetite and as a result encourages weight loss. The drugs belong to a class of medications known as glucagon-like peptide-1 receptor agonists, or GLP-1 RAs, which mimic the GLP-1 hormone, released in the gut after eating some food. The only FDA-approved stomach injections to help with weight management are semaglutide — sold under the brand names Ozempic, Wegovy and Rybelsus — and liraglutide — sold under Saxenda. But others are in development. Helen Knight, programme director of the Centre for Health Technology Evaluation at the National Institute for Health and Care Excellence (Nice) said: “We know that management of overweight and obesity is one of the biggest challenges our health service is facing with nearly two-thirds of adults either overweight or obese. It is a lifelong condition that needs medical intervention, has psychological and physical effects, and can affect the quality of life. “But in recent years Nice has been able to recommend a new line of pharmaceutical treatments which have shown that those people using them, alongside changes to their diet and exercise, have been able to reduce their weight.” How do they work? According to Nice’s independent appraisal committee, drugs like semaglutide should only be prescribed to patients as an alternative for weight management — alongside a reduced-calorie diet and increased physical activity in adults. They should also have a BMI of at least 35.0 kg/m2 (this is medically classified as obese), and especially, to people with a BMI of 30.0 kg/m2 to 34.9 kg/m2, have non-diabetic hyperglycaemia (blood sugar that is above normal but below those needed to diagnose diabetes) or are at high risk of other weight-related conditions such as strokes and heart attacks, due to other factors such as high blood pressure and high cholesterol. Using semaglutide as an example, a typical dose for weight loss is 2.4 milligrams, administered weekly as under-the-skin self-injections. How are they going to be rolled out? Nice formally recommended liraglutide, orlistat and semaglutide as medicines suitable to use for weight loss earlier this year. And with such drugs also available through online pharmacies by private prescription, a growing number of people have tried the jabs. If they are prescribed alongside a reduced-calorie diet, increased physical activity, and behavioural support, after a year, people taking them can lose up to 15% of their body weight, with results visible within the first month, according to the Nice clinical trials. Some weight loss injections are available on the NHS, but they are only prescribed under certain circumstances. Following an announcement of a £40 million two-year pilot on June 7, the government have said more people living with obesity will have access to the newest and most effective obesity drugs to help cut NHS waiting lists. What are the possible side effects? Europe’s drug regulator The European Medicines Agency (EMA) is investigating whether patients using some weight loss and obesity jabs are at risk of suicidal thoughts and thoughts of self-harm, which highlights some of the controversy surrounding the phenomenon. The EMA safety committee said it is looking at cases among people who use a semaglutide or liraglutide-containing medicine for weight loss – where “signals” were raised by the Icelandic Medicines Agency. “A signal is information on a new or known adverse event that is potentially caused by a medicine and that warrants further investigation,” the EMA said. “The case reports included two cases of suicidal thoughts, one following the use of Saxenda and one after Ozempic. One additional case reported thoughts of self-injury with Saxenda. “The semaglutide-containing medicine Wegovy and the liraglutide-containing medicine Saxenda are authorised for weight loss, together with diet and physical activity. “Suicidal behaviour is not currently listed as a side-effect in the EU product information of these medicines.” If you have a history of medullary thyroid cancer, gallbladder disease, or even pancreatitis, you should avoid taking weight loss injections like semaglutide. People who do take the prescription drug for weight loss sometimes experience dizziness, fatigue, and gastrointestinal issues — the most common side effects among patients — such as diarrhoea, constipation and gassiness. They are also at risk of getting headaches and stomach conditions including vomiting, bloating and nausea. Read More Charity boss speaks out over ‘traumatic’ encounter with royal aide Ukraine war’s heaviest fight rages in east - follow live Journalist and author Yomi Adegoke on the real-life consequences of social media What is group B strep? Charity says pregnant women ‘in the dark’ Britney Spears: I worked my ass off to get my memoir written

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Spotting when your child is struggling with their mental health, and knowing how to support them, can be tricky for parents and carers. It’s an important issue to be aware of, however. According to the Children’s Society, in the three years up to 2022, the likelihood of young people having a mental health problem increased by 50%, while children and young people’s mental health charity Place2Be says one in six children experience mental health difficulties, rising to one in four amongst 17–19-year-olds. Emotional disorders including depression and anxiety are among the most common problems to crop up. James Emmett, regional clinical lead at Place2Be, says although the Government has taken “great strides” to address the issue by introducing support teams and senior mental health leads in schools, “we’re still seeing a sharp increase in diagnosable mental health conditions among children and young people, now affecting one in six children – which is around five in every classroom”. Stevie Goulding, senior manager for parents and carers services at the charity YoungMinds, says: “More young people than ever are struggling with their mental health and are in need of support. This generation is facing a unique set of pressures – living through a pandemic, a cost-of-living crisis and ongoing global instability – and they’re worried about their future. “As young people navigate the ups and downs of growing up, recognising when to be concerned about your child’s mental health can be difficult.” Here, Goulding and Emmett outline how parents can spot whether their child may be struggling, and how to help… 1. Look for behaviour changes A change in behaviour is usually the first sign that a child or young person is feeling low, says Emmett: “They may eat too much or not enough, have problems sleeping, or stop doing things they normally enjoy.” Goulding adds: “If you notice changes in your child’s behaviour or if they appear persistently distressed, it could mean they’re struggling with their mental health, and it’s important to take their concerns seriously.” 2. Give them the opportunity to talk Goulding suggests parents try to talk to their child or teen about how they’re feeling in a non-judgemental way. “Remember, they might not want to open up at first, so reassure them you’re there for them when they’re ready to talk. Remind them it’s ok for them to feel scared or unsure, and try to reassure them,” she advises. 3. Don’t force them to talk However, Emmett says sometimes they may not want to talk, adding: “It’s important that adults don’t force them to have a conversation they don’t want to have. Parents and carers must make sure they’re available – but don’t pressure them to talk. “It can be really tempting to ask a lot of questions, but it’s easy to slip into interrogation mode. Try to focus on the here and now and what would help moving forward.” 4. Choose your momentAvoid discussing the underlying causes of your child’s distress with them during intense moments, Goulding advises: “While it’s crucial to provide support, it can be more beneficial to address these topics when they’re feeling calmer.” 5. Ask how they’re feeling Ask if your child notices when they feel more or less sad, for example, at school, or when they’re with their friends and family, suggests Emmett. “Responding sensitively to your child’s signals with concern and interest will help them learn you’re there for them,” he notes. Goulding says parents can acknowledge their child’s feelings by saying something like: ‘It’s completely understandable that you’re feeling…’. She explains: “This helps to reassure them their feelings are valid and it’s ok to feel different emotions.” 6. Remind them of obstacles they’ve overcome in the past When a child or young person gets overwhelmed, they forget just how much they’ve already dealt with in their lives. “Tell them stories about how proud you were when they coped with certain moments in their life, such as an sitting an exam, or moving house,” says Emmett. “This will remind them of their resilience – their ability to adapt to difficult situations.” 7. Encourage them to stay active Physical and mental wellbeing are often linked. “This means doing something active can be a great way to boost your child’s mental health, and heading outside into green space can have even greater benefits,” says Emmett. He suggests parents walk or cycle short distances with their child instead of going in a car: “It’s cheaper and will help the planet to be healthier too.” 8. Model positive relationships Happy relationships between parents and significant adults lead to better mental and physical health for everyone, stresses Emmett. “By modelling positive relationships of your own, you can help your child to see what positive, healthy and meaningful relationships should look like – and to recognise when friendships aren’t positive,” he says. 9. Remind them how they feel will change Your child might not be able to see the light at the end of the dark tunnel they’re in. “Reassure your child that how they’re feeling is temporary,” says Goulding. “Things can change and they can feel better.” 10. Discuss what help is available Talk to your child about the different sources of help that are available, such as helplines, text lines and online chat services. “Reassure them it’s alright to confide in others, as young people often worry about upsetting their parents,” says Goulding. As well as YoungMinds parents’ helpline (0808 802 5544) and Place2Be, other sources include your child’s school, which will have a designated senior mental health lead, your GP who can refer your child to CAMHS, Parenting Smart, which provides free advice for parents and carers of 4–11-year-olds on how to support their child’s wellbeing and behaviour, and the free Shout 24/7 textline for anyone in crisis (text SHOUT to 85258). 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David and Victoria Beckham have celebrated their daughter Harper’s 12th birthday a couple of days earlier with a party at the Prada Caffè in Harrods. The couple’s only daughter will turn a year older on Monday 10 July. She wore a silk lilac slip dress with lace trim from Victoria’s label, with sporty trainers and a sparkly £950 Prada Re-Edition handbag. The proud designer shared snaps from the party on her Instagram account, including a snap of her and Harper with their arms around one another, as well as the birthday girl with her famous footballer father and brothers Romeo and Cruz. Victoria wrote in the caption: “Harper Seven is 12!! (almost) Prada party for Harper Seven CHIC!” Harper was also pictured beaming with a large personalised cake in front of her, with 12 tall white candles waiting to be blown out. Fans praised Harper for her style and wished her a happy birthday. “You can just tell that she’s a genuine good kid! Happy birthday Harper!” one person wrote. Another said: “She’s so tall now! What a lovely young lady she’s become.” The luxurious Prada Caffè features pistachio-coloured walls and interiors, with black-and-white checkerboard floors and marble tables. The themed café opened in March and promises to bring a taste of Milan to Harrods. It comes after Victoria and David marked their 24th wedding anniversary last week with three of their four children. Their eldest son Brooklyn lives in the US with his wife, Nicola Peltz. The couple married on 4 July 1999 in a ceremony at Ireland’s Luttrellstown Castle. They paid tribute to one another on social media by posting throwback photographs of each other and sharing sweet messages. Victoria previously described Harper as her “number one muse” and has created designs especially for her. In January, she shared a mirror selfie of her and Harper, with the then-11-year-old in a strapless ombre gown and sneakers. She wrote: “Mummy loved creating this dress for you.” However, Harper doesn’t always share her former pop star mother’s sartorial tastes. Last year, Victoria revealed just what her daughter thought of the Spice Girls’ iconic miniskirts. Speaking to Vogue Australia, the Spice Girl formerly known as Posh Spice said her daughter is “not one of these kids who are going out with a full face of make-up and a crop top”. “She actually said to me recently, ‘Mummy, I’ve seen some pictures of you when you were in the Spice Girls and your skirts were just unacceptable. They were just too short,” Victoria recalled. “And she was actually quite disgusted at how short my skirts were. “I said, ‘Are you never going to wear skirts like that?’ She said, ‘Absolutely not’. We’ll see.” In the same interview Victoria revealed that she was concerned that Harper will be subjected to body shaming when she is old enough to use social media. She said that her daughter was not allowed on social media yet, but she was concerned about “how cruel people can be”. “She’s at that age where her body is going to start changing, but it’s about making sure that we communicate a lot as a family and she surrounds herself with nice friends,” Victoria said. “But it is quite terrifying, I can’t lie.” Read More Conflict, toxic group chats and organised fun: How we came to despise the hen do Woman exits plane after tirade about passenger who is ‘not real’: ‘Final Destination vibes’ Who is in the Royal Box on the sixth day of Wimbledon? David Beckham pays tribute to Victoria on 24th wedding anniversary Every Barbie-inspired outfit Margot Robbie has worn so far How to make your summer tan last longer

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