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Taking regular Vitamin D supplements may reduce cancer deaths in the population by 15%, according to scientists. Data gathered from the UK Biobank, an online database of medical and lifestyle records of around 500,000 Britons, indicates vitamin D deficiency is linked to an increased cancer mortality risk – particularly in relation to bowel, stomach, prostate, and lung cancers. The researchers said their work, published in Elsevier’s European Journal of Cancer, adds to evidence that vitamin D may have a protective effect against cancer. While the findings do not explain why this happens, the team said one possibility is that vitamin D supplements may induce anti-inflammatory, antioxidant, and DNA damage repair mechanisms, which can thwart mutations that allows tumours to grow. Study author Ben Schottker, an epidemiologist at the German Cancer Research Centre, said: “Our findings identified a statistically significant relationship between vitamin D deficiency and increased mortality among several cancers. “These results can be explained by other studies, which found mechanisms by which vitamin D inhibits cancer growth and metastasis.” The NHS advice is that adults and children over four take a daily supplement containing 10 micrograms of vitamin D throughout the year. According to the Department of Health and Social Care, around one in six adults and almost 20% of children in the UK have vitamin D levels lower than government recommendations. Older people, the housebound and people from black and South Asian communities are more likely to have lower levels of vitamin D. Our findings identified a statistically significant relationship between vitamin D deficiency and increased mortality among several cancers Ben Schottker For the study, the researchers looked at data from more than 400,000 people aged 40–69. In-depth medical information was gathered through blood, urine and saliva samples. A short interview and a questionnaire as used to assess vitamin D consumption as well as lifestyle factors such as alcohol consumption, smoking. Follow-up data on health outcomes were gathered through NHS links as well as care data, cancer screening data, and disease-specific registers. Over a period of nearly 13 years, close to 13,000 people died of cancer. Results showed a majority of the study population had either vitamin D deficiency (21.1%) or insufficiency (34.4%) – used to describe low levels of vitamin D. Of the people involved in the study, only 4.1% regularly took a vitamin D supplement and 20.3% regularly took a multivitamin. Results showed that vitamin D supplement users had 15% lower total cancer mortality and 25% lower lung cancer mortality compared to those who did not take the supplement. The also found researchers found that those with vitamin D deficiency had 42% increased mortality for stomach, 27% for bowel, 24% for lung, and 36% for prostate cancers. Meanwhile those with vitamin D insufficiency were found to have 14% increased bowel cancer mortality and 19% increased lung cancer mortality. The scientists said that the potential to reduce cancer mortality by vitamin D supplementation in populations with low levels should be further explored in new research. Commenting on the study, Dr Jenna Macciochi, senior lecturer in immunology at the University of Sussex, said: “This study adds to the growing body of evidence on vitamin D and cancer. “Vitamin D plays multiple key roles in immune health and the immune system is part of the body’s cancer defence system. “With cancer rates rising and presenting a serious public health issue, its useful to have further insight into the role of vitamin D in the prevention of cancer.” But Dr Macciochi also cautioned that the Biobank data might not be diverse and representative of the whole of the UK population. Alex Ruani, doctoral researcher at University College London and chief science educator at The Health Sciences Academy – who was not involved in the study, said that the exact dosage taken by participants was not ascertained and the risk reduction was not the same for all cancers. She said: “This research doesn’t imply that taking vitamin D3 supplements will for sure lower your risk of death from cancer. “Supplementation may help with consistent vitamin D levels, whereas production from sunlight can be variable and dependent on weather, time of the day, exposure duration, being outdoors or indoors, protective UV wear or sunblock, and many other factors.” She added: “Common food sources of vitamin D3 include full-fat dairy, egg yolks, and fish. “Although toxicity is rare, there is an upper tolerable limit set in the UK, where vitamin D3 supplementation shouldn’t exceed 100 micrograms a day.”

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Some may argue that the most difficult part of dating apps is putting a profile together – well, one of them at least. That's before the love bombing, ghosting and a string of other modern dating behaviours come into play. For the first time since 2020, Hinge has revealed the 25 most successful Prompts, based on how often they lead to a conversation. The insight is a fun look into dating today and the creative way daters are expressing themselves on their profiles. It showcases some of the ways daters are stepping out of their comfort zone to show their most authentic selves. Before we launch into them, Hinge's director of relationship science, Logan Ury (she/her) offered three tips to get the most out of your online profile. Try using your voice if you're struggling with what to write Hinge’s Voice Prompts feature is one of the most authentic ways you can express yourself on your profile. 64 per cent of daters feel a potential match’s voice is an important factor in determining if they like them and almost half (49 per cent) of users have become more attracted to someone after hearing their voice. Be Yourself Successful profiles include a mixture of both humour and vulnerability, so lean into both your silly side and your more serious one. If you want to use the ‘The Way to Win Me Over’ Prompt, dig deep and think of something original and unique to you. Stop talking about your love for “The Office” and start telling us about your secret hobby as a herbal tea connoisseur. The Perfect Prompt Answer the Prompts in a way that encourages more in-depth conversation and leads to more meaningful connections. In other words, no one-word answers, please! Whatever it is you love about who you are, make sure other people can see it. This will help you present your authentic self. Your profile should be an extension of your personality. Ideally, your Prompts should give someone a sense of what you’re like and what it would be like to date you. Paint a picture of who you are by mentioning specific quirks or pleasures can help create a vivid image of who you are and help them picture what a relationship with you would be like. Still not sure where to start? Try using one of the following most successful prompts on the platform: The way to win me over is My simple pleasures I go crazy for Together, we could My most irrational fear We'll get along if I'm looking for This year, I really want to Typical Sunday A life goal of mine My greatest strength Dating me is like I’m convinced that I want someone who Unusual skills The key to my heart is First round is on me if What if I told you that I’m weirdly attracted to My Love Language is All I ask is that you I’ll fall for you if I won’t shut up about The one thing you should know about me is I bet you can’tSign up for our free Indy100 weekly newsletter Have your say in our news democracy. Click the upvote icon at the top of the page to help raise this article through the indy100 rankings.

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“Television is art,” screenwriter Sierra Teller Ornelas tells Refinery29 Somos. “It’s not meant to be made like a car.” If anyone knows the amount of creativity required for television writing, it’s her. She’s spent the last decade working on television shows like Brooklyn Nine-Nine and NBC’s Superstore, including leading her own production in Peacock’s much-loved but short-lived Rutherford Falls. She was recently developing a Latine sitcom for NBC called Amigos, but she’s not working now — she, along with thousands of others, is on strike with the Writers Guild of America (WGA). And this week, the group was recently joined by the 160,000-person-strong actor union, SAG-AFTRA.

A mother who was diagnosed with skin cancer while pregnant during the first summer of the Covid-19 pandemic has urged Scots to “enjoy the warm weather safely”. Andrea Lambrou, of Newlands, Glasgow, was 36 weeks pregnant in July 2020 when doctors informed her she had malignant melanoma – the most serious form of skin cancer. Her diagnosis transformed what was previously one of the happiest and exciting times in her and husband Nicos’s lives into a nightmare. The remaining days of her pregnancy were spent in and out of hospital for appointments and treatment. After a 24-hour induction, 17 hours in the labour room and an emergency C-section, her son Leo was born prematurely on July 24. Lambrou, 39, first became alarmed when she noticed a dark freckle on her leg which appeared to have grown in size, and she was referred to the dermatology department at the Queen Elizabeth University Hospital in Glasgow. The mole was removed the same day, but a week later she was told she had cancer. She said: “I’ll never forget hearing those words – not ‘I’m sorry, you have cancer’, but what came next: ‘We have to get that baby out now.’ “I had no choice. It was just as well I didn’t have a birth plan as there was no time to get my head around anything.” Around four people in Scotland are diagnosed with malignant melanoma every day, which is about 1,400 people a year. UK-wide, the figure has reached a record high of 17,500 cases a year and the numbers are projected to increase by 50% over the next 20 years, according to cancer research. Lambrou’s cancer is now in remission and, alongside Cancer Research and Nivea Skin, she is encouraging people to take precautions to minimise the risk of getting skin cancer. She said: “I hope by sharing my story I can raise awareness about sun safety and about early detection. “After three major surgeries in the first six months of motherhood and a year-and-a-half of immunotherapy treatment, I showed clear scans and I continue to do so. “The positivity just shines from our little Leo. I couldn’t have asked for a happier, funnier, more beautiful smiley wee boy. “But there was trauma and tears when I was first given the news that I had skin cancer. I couldn’t believe this was happening to me. “I hope I can encourage people to think about their sun habits and take precautions. “It’s so important, because almost nine in 10 melanoma cases each year in the UK could be prevented by being safe in the sun and using a combination of shade, clothing and sunscreen to avoid burning.” She recommends seeking shade between 11am and 3pm in the UK, when the sun’s UV rays are at their most harmful. She also suggests wearing clothes that cover the skin properly, such as long-sleeved tops, sunglasses and wide-brimmed hats. Sunscreen over SPF 15 is also recommended. The month after Leo’s birth, a large area of skin across Lambrou’s leg and knee was removed and she had a lymph node biopsy, which confirmed her cancer had spread. After starting immunotherapy, she noticed a marble-sized lump near her groin around Christmas 2020. In January 2021 she went through another operation to remove the lymph nodes in her groin area. She was also kept in hospital after developing cellulitis, a series skin infection. The mother said: “It hit me like a ton of bricks. I genuinely thought I was going to die.” But by Easter 2021, she was told she was cancer free. She said: “If you spot something on your skin that’s not right for you, get it checked out.” Beth Vincent, health information manager at Cancer Research UK, said: “Melanoma skin cancer is the UK’s fifth most common cancer, so we’re grateful to Andrea for lending her voice to our campaign with Nivea Sun. “It’s important to remember the sun isn’t only strong abroad. Even on a cloudy day, it can be strong enough in Scotland – and across the UK – to burn between mid-March and mid-October.” Read More Woman exits plane after tirade about passenger who is ‘not real’: ‘Final Destination vibes’ Kevin Costner’s estranged wife slams ‘inappropriate’ $52k child support payment Florence Pugh makes return to Paris Fashion Week in transparent dress following last year’s uproar Warning as skin cancer cases reach record high Best sunscreen for your face 2023: Daily SPF protection, from sensitive to non-greasy formulas

Canadian Prime Minister Justin Trudeau is separating from his wife Sophie after 18 years of marriage, the couple