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A new, first-of-its kind study has demonstrated that laughter can indeed be good medicine – especially for those with heart disease. Laughter therapy can increase the functional capacity of the cardiovascular system that includes the heart, lungs, arteries and veins, found the yet-to-be peer-reviewed research presented at the annual meeting of the European Society of Cardiology in Amsterdam. Researchers, including Marco Saffi from the Hospital de Clínicas de Porto Alegre in Brazil, found reduced inflammation and better signs of health among coronary artery disease patients who engaged in a course of laughter therapy. They found laughter therapy sessions could cause the tissue inside a patient’s heart to expand, potentially leading to increased oxygen flow through the body. Until now, different treatments without the use of drugs have been studied in coronary artery disease patients, but the benefits of rehabilitation using laughter therapy was not fully assessed, scientists said. In the new study, the impact of laughter therapy on the functional capacity, tissue function as well as markers of inflammation in the bodies of patients with coronary artery disease was evaluated. The condition, which is one of the most common diseases in the world, arises when the heart’s coronary arteries struggle to supply the organ with enough blood, oxygen and nutrients. Scientists conducted a clinical trial involving 26 adults with an average age of 64 from August 2016 to December 2020, measuring each of their oxygen uptake and the widening of their main artery when blood flow increases. Researchers also measured levels of molecules in the patients’ bodies, indicative of inflammation such as interleukin (IL)-6, IL-10, tumour necrosis factor (TNF)-alpha, vascular cell adhesion molecule (VCAM) and intercellular adhesion molecule (ICAM). Thirteen of the patients were assigned to the group that underwent laughter therapy by watching two self-selected TV comedy shows per week. The other 13 served as the control group and watched “neutral documentaries”, scientists noted. They said the study is the first controlled clinical trial to evaluate the impact of rehabilitation using laughter therapy on patients with coronary artery disease. It revealed an increase in the body’s peak oxygen uptake and improvements in tissue function as well as the body’s markers of inflammation. The new findings are in line with previous research that suggested having a good laughter session makes the body release endorphins, which are hormones that reduce stress and inflammation and help the heart and blood vessels relax. Based on the new results, presented at the world’s largest heart conference, scientists say laughter therapy may constitute an “effective form of cardiac rehabilitation in this patient population”. Read More How many steps a day can cut risk of early death (and it’s not 10,000) A broad genetic test saved one newborn's life. Research suggests it could help millions of others Snoring before age 50 is a health ‘red flag’, experts suggest How many steps a day can cut risk of early death (and it’s not 10,000) Experts warn that snoring before you turn 50 is a health ‘red flag’ ‘Boy moms’ called out for dubious logic behind teaching their sons to cook

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Lewis Hamilton has told Max Verstappen to stop complaining after his rival criticised Formula One’s maiden race on the Las Vegas strip as “99 per cent show, and one per cent sport”. Verstappen’s controversial remarks – which will irk F1’s American owners’ Liberty Media following their estimated £400million gamble to bring the sport back to Sin City for the first time in 41 years – arrived just moments after a glittering Superbowl-style opening ceremony on Wednesday night. John Legend and Kylie Minogue were among a number of high-profile artists to perform in a dazzling 30-minute show designed to kick-start the penultimate round of the season, billed as the greatest show on earth. The grid’s 20 drivers were also presented to the crowd ahead of Saturday night’s 50-lap race which F1 executives are using to build on the sport’s growing popularity in the United States. The race in Nevada joins Austin and Miami as the third in America. But moments after a fireworks display brought the curtain down on the glittering welcome party, Verstappen, crowned triple world champion in Qatar last month, was quick to pour scorn on the event. “It is 99 per cent show and one per cent sporting event,” said the 26-year-old. “I was just standing up there, looking like a clown. “I guess they (F1) still make money whether I like it or not. So it’s not up to me. But I’m not going to fake it. “I voice my opinion on positive things and negative things. That’s just how I am. And you know, some people like the show a bit more. I don’t like it at all. “I grew up just looking at the performance side of things. And that’s how I see it as well. I like to be in Vegas, but not so much for racing.” However, responding to criticism, Hamilton, 38, said: “I hear there are a lot of people complaining about the direction that (F1 CEO) Stefano (Domenicali) and Liberty has gone. But they are doing an amazing job. “The sport continues to grow. It is a business and you will still see good racing here. It is a country to tap into and really captivate the audience. “We needed to have at least two races in the US, one wasn’t enough, and this is one of the most iconic and unique cities that they have here. “It is a big show for sure, and it is never going to be like Silverstone, but maybe over time, the people in this community will grow to love the sport. “Maybe the track will be good, and maybe it will be bad. It was so-so on the simulator. But don’t knock it until you try it.” The debut race on the strip, which starts at 10pm local time, comes after three consecutive rounds in Austin, Mexico and Brazil and ahead of next weekend’s concluding race in Abu Dhabi – a weary time swing of 12 hours. The circuit itself features 17 corners over 3.8 miles along the famous Las Vegas Boulevard, and against the backdrop of Caesars Palace, the Venetian and the Bellagio. It is expected that the drivers will hit speeds in excess of 210mph, but Verstappen said: “The track is not very interesting with not many corners. “It will depend a little bit on how grippy it is. It doesn’t look like there’s much grip.” Verstappen has won 17 of the 20 rounds so far, while it is approaching two years since Hamilton, in his Mercedes, has tasted victory. Hamilton, who will get his first taste of the street track in opening practice at 8:30pm local time on Thursday (4:30am GMT on Friday) continued: “From a racer’s perspective, you want to have the best show here. “If the track provides a race like Baku – which is one of the best races with lots of overtaking – than that would be amazing, rather than just one car disappearing into the distance. “Everybody I know in Hollywood is coming and there will be a lot of business going on this weekend. “It will be a good spectacle to watch, even for those back home who have never been to Vegas. They will get to learn what it is all about.” Read More Toto Wolff fuelled by ‘personal anger’ to help Lewis Hamilton win eighth title On this day in 2010: Sebastian Vettel becomes youngest ever F1 world champion Lewis Hamilton ‘counting down days’ to end of season after another poor race Max Verstappen thwarts Lando Norris’ bid for first F1 win with sprint victory On this day in 2015: Susie Wolff ends her bid to get on an F1 starting grid Lando Norris ‘gutted’ to miss out on Brazilian GP pole after McLaren blunder

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