Whisky believed to be 189 years old up for auction after being found in Scottish castle
One of the world’s oldest whiskies will be auctioned off after being discovered in a Scottish castle. The whisky was found behind a cellar door at 750-year-old Blair Castle, Perthshire, the ancestral home of the Dukes of Atholl. Around 40 bottles of the rare Scotch whisky, said to be one of the oldest in the world, were discovered in late 2022 when Bertie Troughton, a resident trustee at Blair Castle, happened upon them in the cellar. They are believed to have been distilled in 1833, bottled in 1841, then later rebottled in 1932.
2023-09-28 03:59
Heavy rains bring deadly flash flood and landslide to northwest China
At least 21 people are dead and six others missing after a flash flood and landslide following torrential rains in the outskirts of northwestern China's Xi'an city, local authorities said Sunday.
2023-08-14 13:58
Scientist behind Ozempic says drug can make life ‘so miserably boring’
One of the scientists whose work pioneered the development of medications such as Ozempic and Wegovy has revealed why life may become “so miserably boring” after two years of using the drug. Ozempic is an FDA-approved medication used for the treatment of type 2 diabetes. It works by mimicking a hormone called glucagon-like peptide 1 (GLP-1), which regulates blood sugar levels and slows down the rate at which food leaves the stomach, often creating the feeling of fullness. These semaglutide injections – sold under the brand names Ozempic and Wegovy – have soared in popularity as many people, including Hollywood celebrities, have used it for weight loss. What’s more, people have also found Ozempic has been effective in curing their addictive habits, like drinking, smoking, shopping, or nail biting. However, because of Ozempic’s increasing popularity, it has led to national shortages of the type 2 diabetes treatment – leaving those who actually need it without. In an interview with Wired, professor Jens Juul Holst – who received the Warren Alpert Foundation Prize in 2021 for his work developing treatments based on the GLP-1 hormone – spoke about the effects of Ozempic, and why he believes many people will stop taking the medication after just a few years. “What happens is that you lose your appetite and also the pleasure of eating, and so I think there’s a price to be paid when you do that,” Holst told Wired. “If you like food, then that pleasure is gone. The craving for food for some people is taken away when they take GLP-1 drugs.” He continued: “That may eventually be a problem, that once you’ve been on this for a year or two, life is so miserably boring that you can’t stand it any longer and you have to go back to your old life.” Holst added that medications like Ozempic and Wegovy have been on the market since 2005, though studies show that these people don’t stay on them for very long. “It’s just like every other drug, they don’t stay on it for many reasons,” he explained. “One of the reasons, as I said, is that once you have tried it and you realise you’ve lost interest in food, then that may be enough.” “We don’t know why people stop taking these drugs, but we know for a fact that they do stop. They do that all over the world.” A 2020 study found that 70 per cent of people who took GLP-1 drugs for type 2 diabetes stopped taking them within two years. However, this could pose a problem for many patients taking semaglutide injections. Research has found that people who stopped taking Ozempic or Wegovy for weight loss experienced weight rebound. A trial published in April 2022 saw participants gain back two thirds of the weight they had lost after 68 weeks of taking semaglutide. As for celebrities who use the once-weekly injection for weight loss, despite not having diabetes or clinical obesity, Hans instead called attention to the “many terrible problems” that those with diabetes have struggled with by not having drugs like Ozempic readily available. “Have you ever visited a diabetes hospital? It’s really deplorable,” he said. “People come in with amputated limbs and compromised cognitive functions and heart problems or they can barely move – they’re miserable and depressed. It’s really serious. There is so much you can improve with a drug that is not only a weight-loss drug but is also an anti-diabetic.” Amidst the popularity of semaglutide injections, the US Food and Drug Administration has issued warnings for consumers not to use off-brand versions of Ozempic or Wegovy, because they may not include the same GLP-1 hormone used in approved medications. Earlier this month, agency officials reported problems with patients using compounded versions of semaglutide – which combines traditional semaglutide with other ingredients. These drugs are not FDA-approved, and the agency does not verify the safety or effectiveness of compounded drugs. Consumers should only use drugs containing semaglutide with a prescription from a licensed health care provider and obtained from a state-licensed pharmacy or other facilities registered with the FDA, the agency said. Read More What is ‘Ozempic face’? Doctors warn about facial ageing side effect of diabetes medications How does Wegovy work? The ‘game changing’ weight loss drug beloved by Hollywood FDA warns against using off-brand versions of Ozempic, Wegovy for weight loss Pregnant Stassi Schroeder admits she wants to ‘try’ Ozempic after giving birth Doctors warn about ‘Ozempic face’ side effect of medications Amy Schumer says she stopped taking Ozempic because of side-effects
2023-06-16 23:52
Quick, tidy up! They're here: San Francisco scrambles for APEC
Like a housework-shy couple who suddenly discover the neighbors are dropping round, San Francisco is in tidying panic mode as it readies for...
2023-11-13 09:51
Positive results for potential first chikungunya vaccine
French-Austrian drugmaker Valneva's vaccine candidate against chikungunya, a mosquito-borne virus that causes occasional outbreaks across the world, showed promising results in a large new trial...
2023-06-13 16:51
Onanoff BuddyPhones Pop Fun Review
The $39.99 Onanoff BuddyPhones Pop Fun offer everything we expect from a pair of kids'
2023-11-21 05:22
Gwyneth Paltrow’s daughter Apple Martin revives her infamous 2002 Oscars dress
Gwyneth Paltrow has revealed that she still owns her infamous 2002 Oscars dress that “everybody hated,” and that her daughter Apple Martin even wears it on occasion. The Goop founder, 50, took to Instagram on Thursday 15 June to answer some questions from her fans and followers – including what she ate for breakfast and her go-to restaurant recommendations. When one fan asked Paltrow if her daughter Apple wears “any of [her] fashion archives,” the Shakespeare in Love star responded with a photo of the 19-year-old model dressed in the memorable Alexander McQueen gown, which Paltrow wore to the 2002 Academy Awards. In the snap, Apple – who Paltrow shares with ex-husband and Coldplay frontman, Chris Martin – could be seen standing in her mother’s walk-in closet while posing with one hand under her chin and the other on her hip. Back in 2002, the gothic Alexander McQueen dress caused quite a stir for its sheer, sleeveless bodice. The punk-inspired black gown also featured a flowing black floor-length skirt. Gwyneth Paltrow has previously discussed the criticism she received after attending the 2002 Oscars in the daring gown. In 2021, the Glee alum revisited some of her most iconic fashion moments, including the criticism she received for the black McQueen dress. “Everybody really hated this [dress] ... but I think it’s kind of dope,” she said in a video interview with Vogue. “I’m into it.” However, the lifestyle guru admitted she was hurt by the criticism over the dress at the time. “I had a weird hangover about it for a while because people were really critical,” Paltrow explained. “I think at the time it was too goth, I think people thought it was too hard, so I think it sort of shocked people. But I like it.” Paltrow also defended the dress – which was then dubbed “unflattering” and “a fashion disaster” – in a Q&A post shared to Goop’s website in 2013. “I still love the dress itself but I should have worn a bra and I should have just had simple beachy hair and less makeup,” she said. “Then, it would have worked as I wanted it to – a little bit of punk at the Oscars.” Apple Martin has since become somewhat of a fashion icon herself. Earlier this year, she made her Paris Fashion Week debut at the Chanel haute couture spring/summer 2023 show in January. For the occasion, Apple was pictured sitting front row in a black-and-white tweed skirt and jacket set by Chanel. The teen recently poked fun at the Iron Man star after she made some candid confessions about her love life during an episode of the Call Her Daddy podcast. In a video shared to the official Call Her Daddy Instagram account, Apple could be seen standing next to her mom and host Alex Cooper, as Paltrow shared many NSFW details about exes Brad Pitt and Ben Affleck. Apple proceeded to cover her ears as her mom divulged about her past relationships. “When your mom goes on Call Her Daddy,” the text over the clip read, along with a crying face emoji. In addition to daughter Apple, Paltrow shares 17-year-old son Moses with ex Chris Martin. These days, the entrepreneur is married to producer Brad Falchuk, while the Coldplay singer has been dating actor Dakota Johnson since 2017. Read More Gwyneth Paltrow recalls being hurt by criticism of 2002 Oscar dress that ‘everybody hated’ Apple Martin hilariously reacts to Gwyneth Paltrow’s candid confessions about love life on Call Her Daddy Apple Martin opens up about attending first fashion show and her ‘classic ‘90s’ style
2023-06-16 06:54
Jennifer Lopez rocks vibrant maxi dress as singer goes for lunch with twins Max and Emme in LA
In the spring of 2021, the dancer rekindled her romance with Ben Affleck and tied the knot in Las Vegas in July 2022
2023-06-11 18:58
Twitter's Advertiser Exodus Could Cost The Company $75 Million
If advertisers continue to pause their spending on Twitter/X, the company might lose up to
2023-11-26 01:19
Czech News Crew Robbed While Filming in San Francisco for APEC Summit
San Francisco’s push to use a major international conference to reverse its image as a city in decline
2023-11-14 08:58
Best Buy is reviving its 'Black Friday in July' sale to give Prime Day a big run for its money
It was a matter of when, not if, Best Buy announced some conveniently scheduled counter-programming
2023-06-24 01:22
Up at 3:00 am: World Cup players in losing battle with jet lag
Every long-distance flyer knows how debilitating jet lag can be, but now imagine you need to train right away and then play...
2023-07-19 17:46
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