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With new research emerging, more questions have been raised about weight-loss injections, how they work, and the risks involved. Here are some of your questions answered. What are weight loss injections? Championed by some celebrities, including Elon Musk, weight loss injections were originally created to treat people with type 2 diabetes and other weight-related health issues. They are a type of prescription-based medical treatment that interferes with your metabolism, regulates your appetite and as a result encourages weight loss. The drugs belong to a class of medications known as glucagon-like peptide-1 receptor agonists, or GLP-1 RAs, which mimic the GLP-1 hormone, released in the gut after eating some food. The only FDA-approved stomach injections to help with weight management are semaglutide — sold under the brand names Ozempic, Wegovy and Rybelsus — and liraglutide — sold under Saxenda. But others are in development. Helen Knight, programme director of the Centre for Health Technology Evaluation at the National Institute for Health and Care Excellence (Nice) said: “We know that management of overweight and obesity is one of the biggest challenges our health service is facing with nearly two-thirds of adults either overweight or obese. It is a lifelong condition that needs medical intervention, has psychological and physical effects, and can affect the quality of life. “But in recent years Nice has been able to recommend a new line of pharmaceutical treatments which have shown that those people using them, alongside changes to their diet and exercise, have been able to reduce their weight.” How do they work? According to Nice’s independent appraisal committee, drugs like semaglutide should only be prescribed to patients as an alternative for weight management — alongside a reduced-calorie diet and increased physical activity in adults. They should also have a BMI of at least 35.0 kg/m2 (this is medically classified as obese), and especially, to people with a BMI of 30.0 kg/m2 to 34.9 kg/m2, have non-diabetic hyperglycaemia (blood sugar that is above normal but below those needed to diagnose diabetes) or are at high risk of other weight-related conditions such as strokes and heart attacks, due to other factors such as high blood pressure and high cholesterol. Using semaglutide as an example, a typical dose for weight loss is 2.4 milligrams, administered weekly as under-the-skin self-injections. How are they going to be rolled out? Nice formally recommended liraglutide, orlistat and semaglutide as medicines suitable to use for weight loss earlier this year. And with such drugs also available through online pharmacies by private prescription, a growing number of people have tried the jabs. If they are prescribed alongside a reduced-calorie diet, increased physical activity, and behavioural support, after a year, people taking them can lose up to 15% of their body weight, with results visible within the first month, according to the Nice clinical trials. Some weight loss injections are available on the NHS, but they are only prescribed under certain circumstances. Following an announcement of a £40 million two-year pilot on June 7, the government have said more people living with obesity will have access to the newest and most effective obesity drugs to help cut NHS waiting lists. What are the possible side effects? Europe’s drug regulator The European Medicines Agency (EMA) is investigating whether patients using some weight loss and obesity jabs are at risk of suicidal thoughts and thoughts of self-harm, which highlights some of the controversy surrounding the phenomenon. The EMA safety committee said it is looking at cases among people who use a semaglutide or liraglutide-containing medicine for weight loss – where “signals” were raised by the Icelandic Medicines Agency. “A signal is information on a new or known adverse event that is potentially caused by a medicine and that warrants further investigation,” the EMA said. “The case reports included two cases of suicidal thoughts, one following the use of Saxenda and one after Ozempic. One additional case reported thoughts of self-injury with Saxenda. “The semaglutide-containing medicine Wegovy and the liraglutide-containing medicine Saxenda are authorised for weight loss, together with diet and physical activity. “Suicidal behaviour is not currently listed as a side-effect in the EU product information of these medicines.” If you have a history of medullary thyroid cancer, gallbladder disease, or even pancreatitis, you should avoid taking weight loss injections like semaglutide. People who do take the prescription drug for weight loss sometimes experience dizziness, fatigue, and gastrointestinal issues — the most common side effects among patients — such as diarrhoea, constipation and gassiness. They are also at risk of getting headaches and stomach conditions including vomiting, bloating and nausea. Read More Charity boss speaks out over ‘traumatic’ encounter with royal aide Ukraine war’s heaviest fight rages in east - follow live Journalist and author Yomi Adegoke on the real-life consequences of social media What is group B strep? Charity says pregnant women ‘in the dark’ Britney Spears: I worked my ass off to get my memoir written

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The formula for the perfect fish finger sandwich has been revealed: it's made with four fish fingers, 'real' butter, two slices of white bread, ketchup... and cut sideways.  A poll of 2,000 adults who eat fish finger sandwiches found that 42 per cent said it was their sandwich of choice.  According to those polled, the optimum fish finger sarnie is also made with lettuce (21 per cent), cheese (15 per cent) and tomato (12 per cent).  Nearly half (43 per cent) like their sandwich to be cut sideways, so there are whole fish fingers on both sides of the bread. But 30 per cent like to cut their sarnie lengthways, so all fish fingers are in half, and nine per cent go as far as cutting everything into triangles. Commissioned by Birds Eye, The Marine Stewardship Council (MSC), and Iceland Foods, which sells MSC certified products like Birds Eye fish fingers, the study found 76 per cent would opt for a fish finger sandwich made from sustainably sourced cod.  A spokesperson for the supermarket chain said: "We know our fish fingers are not only great value, but they taste good too - making them a quick and easy meal that is guaranteed to be a crowd pleaser for families. "With one third of the world's fish stocks overfished, it is more important than ever for shoppers to choose seafood from sustainable sources." Exactly nine in 10 said the fish finger sandwich is a quick, easy and affordable meal that tastes good. In addition, just over two thirds (68 per cent) said they care about making mealtimes more sustainable. But 62 per cent claim they only have a vague idea of what sustainable fishing is. Encouragingly, 80 per cent correctly believe the process of sustainable fishing ensures fish are left in the ocean, impact on habitats and ecosystems is minimalised, and fisheries are effectively managed. However, one in 16 mistakenly think sustainable fishing happens once a year so there is enough fish left in the ocean for everyone else. When asked to describe the meaning of the blue MSC label, 42 per cent were “unsure”. However, 44 per cent rightly said it is the symbol of sustainability for wild-caught fish and seafood. More than half (55 per cent) said they care about the impact their food choices have on the planet but find it confusing, while 39 per cent of those who took part in the OnePoll.com study simply can’t afford to make the necessary changes. A spokesperson for MSC said: "The creators of the fish finger, Birds Eye, helped to co-found the MSC to help protect seafood supplies. While Iceland, who won MSC UK Newcomer of the Year in 2020, has made great progress in increasing the availability of sustainable seafood to its customers. "And now offers the highest percentage range of MSC certified wild seafood among all UK retailers.” A spokesperson for Birds Eye added: “We are very proud to be working closely with the MSC. Fish is good for our health, and so for the good of our oceans the Birds Eye fish range is 100 per cent MSC certified to make sure future generations can enjoy fish too.” SWNS Read More Order a bagel and schmear at Feltz Bagels, and you'll be fed an original piece of art Kale, crispy bacon upgrades grilled cheese to an adult level Six healthy recipes that both you and your gut will love Being vegetarian may partly be in one’s genes, study finds Jamie Oliver says he’d choose anonymity over fame if given the choice again

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A new poll has found that 12% of people still believe that drinking coffee is carcinogenic. The new poll – conducted by the World Cancer Research Fund (WCRF), which surveyed 2,092 adults via YouGov – looked into the different ways people live, and whether it impacts their risk of cancer. The research found that 86% of people believed smoking increased the risk of cancer, while 60% said that being overweight could do the same. 47% thought being physically inactive can be detrimental, and 59% believed a poor diet can up the odds. Almost 59% said alcohol can increase a person’s risk and 55% said processed meat could be a risk factor. WCRF launched its poll to highlight its free eight-week interactive programme Activ8, to provide people with tips on making healthier food and drink choices, and finding different ways to be more active. Cancer Research UK wrote on their website that “not all cancers can be prevented, but there are things you can do to reduce your risk”. A person’s risk of cancer depends on many different things, for example, someone’s genes or age. But according to the charity, four in 10 UK cancer cases could be prevented. “The world around us doesn’t always make it easy to be healthy – but small changes to your daily routine can add up.“ The WCRF agreed and has said that around 40% of cancer cases could be prevented through factors including eating a healthy diet, keeping physically active, maintaining a healthy weight, not smoking and being safe in the sun. Dr Helen Croker, assistant director of research and policy at the WCRF, said: “These poll results show that many people aren’t aware of some of the steps they can take to help protect themselves from cancer. “For example, it’s interesting to see that 12% of Brits believe drinking coffee increases cancer risk, when in fact we have strong evidence that it reduces the risk of liver and womb cancers, and some evidence that drinking coffee could decrease the risk of other cancers, including mouth and skin. “For cancer prevention, there’s no reason for most people not to drink coffee, but for those who do, we recommend not adding sugar or other sweeteners, and drinking it in moderation.” Read More Charity boss speaks out over ‘traumatic’ encounter with royal aide Ukraine war’s heaviest fight rages in east - follow live A-Level results: How to be the emotional support your teen really needs These are the cheapest school uniforms on the high street – according to Which? Half of anxiety and depression cases in new and expectant mums are missed: 7 signs a new mum needs help

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