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Imani Futrell was 11 years old when she first noticed a tiny bump on her groin. She thought nothing of it, but before long, another surfaced on her underarm — then another on her buttocks. Soon, those tiny bumps grew into large cysts that she felt she had to cover up with surgical bandages. It would be another five years before Futrell went to her doctor to find out what was going on.

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Women with myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) tend to have more symptoms and co-occurring conditions than men, according to the world’s largest study of the disease. The study, entitled DecodeME, reveals women who have the condition for more than 10 years are more likely to experience increasingly severe symptoms as they get older. ME/CFS is estimated to affect more than 250,000 people in the UK, of all ages and from all social and economic backgrounds. Its key feature, called post-exertional malaise, is a delayed dramatic worsening of symptoms following minor physical effort. Other symptoms include pain, brain fog and extreme energy limitation that does not improve with rest. Causes are unknown and there is currently no diagnostic test or cure. Experts from the University of Edinburgh analysed anonymous survey questionnaires from more than 17,000 people with ME/CFS. Two-thirds of women, and slightly more than half of men, reported at least one active co-occurring condition. Similarly, 39.2% of women and 28.6% of men reported at least one inactive co-occurring condition. We discovered that the disease is worse for women, in older people, and many years after their ME/CFS started Professor Chris Ponting of the University of Edinburgh A condition was considered active if the participant had experienced symptoms in the preceding six months. The most common active co-occurring condition was irritable bowel syndrome, with clinical depression, fibromyalgia, anaemia and hypothyroidism also featuring prominently. Women also reported, on average, more symptoms than men – 42 compared with 36. The most common of these symptoms were brain fog – a term commonly used to describe the cognitive impairment experienced by participants – unrefreshing sleep and muscle pain. These findings highlight the very serious impact ME/CFS has on women who are disproportionately affected Sonya Chowdhury, chief executive of Action for M.E Participants were also asked to define the severity of their illness from mild to very severe using definitions from the UK’s National Institute for Health and Care Excellence guidelines. Experts identified that being a woman and having ME/CFS for more than 10 years are risk factors for severe illness, with symptoms increasing in intensity as they age. Professor Chris Ponting, study lead from the MRC human genetics unit at the University of Edinburgh’s Institute of Genetics and Cancer, said: “ME/CFS is a devastating disease affecting a UK population the size of Derby. “We discovered that the disease is worse for women, in older people, and many years after their ME/CFS started. “Our hope is that DecodeME’s genetic results will shed light on why certain groups are more susceptible to ME/CFS than others.” Sonya Chowdhury, chief executive of Action for M.E. and chair of the management group of the study, said: “These findings highlight the very serious impact ME/CFS has on women who are disproportionately affected. “It’s important to also recognise the impact that it has on men who have ME/CFS and we thank the 20,000 men and women who have already signed up to take part in this very important study. “We still need more to join us, so if you are 16 or older, live in the UK and have a diagnosis of ME/CFS, please do take part now to help us decode ME at www.decodeme.org.uk/portal.” Read More Charity boss speaks out over ‘traumatic’ encounter with royal aide Ukraine war’s heaviest fight rages in east - follow live 4 hacks to get teens off the sofa and get active – as study warns of heart damage Taking adult education classes may lower risk of dementia, study suggests Indiyah Polack: I didn’t want to go on Love Island because of my acne

With the release of the Barbie movie fast approaching on July 21, the marketing campaign has been unavoidable. From the pink billboards to the endless amount of brand collaborations - everyone and everything is channelling Barbie this summer. This includes Barbie herself, Margot Robbie who is taken fashion inspiration from the different looks the Mattel doll has worn over the years to wear at different premieres. Sign up to our free Indy100 weekly newsletter Of course, fans are loving the way the Australian actor is paying homage to her character. One person said: "I literally can't even with the perfect Barbie looks that Margot Robbie has been sporting on her Barbie press tour." "It’s so unbelievably perfect. She [Robbie] gave everything I wanted and more. Need this energy from the other characters," another person wrote. Someone else added: "Margot Robbie is slaying the #barbie promo tour so hard it's almost painful." "Margot Robbie turned Barbie into the fashion event of the year and I am here ittttt," a fourth person commented. Here is a rundown of all Robbie's Barbie-inspired looks during the Barbie movie press tour: Cinemacon, Las Vegas (April 25 2023) Robbie hinted at her Barbie wardrobe at Cinemacon back in April where she sported a pink gingham Prada bralette and skirt set based on a dress her character wears in the film. Since then, Mattel has created this outfit for Barbie dolls, so you could say the film was the inspiration in this case. Los Angeles photo call (June 25 2023) Barbie loves all things pink, including a pink dress with white polka dots. This fun Valentino number accessorised with a bright yellow bag took inspiration from the 2015 Pink & Fabulous Barbie. Sydney, Australia photo call (June 29 2023) Throwing it back to Barbie's first-ever outfit with the black-and-white swimsuit, Robbie took inspo and wore a black-and-white Hervé Léger dress with white sunglasses to match during a photo call on Bondi Beach. This swimsuit can also be seen on Robbie in the Barbie movie trailer too. Barbie Celebration party, Sydney (June 30 2023) Sparkling in a dazzling metallic pink 1994 Versace dress, Robbie's outfit channeled a similar outfit to the Happy Birthday Barbie - and while it might not be Robbie's birthday, she had plenty to celebrate at the Barbie party in Sydney. Seoul 'Barbie' premiere, South Korea (July 2 2023) Dress up with a white brimmed hat, hot pink blazer, pencil skirt and high heels - not forgetting the rhinestone phone - Robbie's outfit was a throwback to the 1985 Day-to-Night Barbie, with this being the day look. Robbie later changed into the night look which was a pink sparkly leotard and a part-Versace pink dress with the tutu skirt. Media news conference, Seoul (July 3 2023) It was pink and sparkles galore for Robbie at a media conference in Seoul when she turned up for the event in a bejewelled suit skirt set, with a cute hair bow and heart bag to match in tribute to the 1964 Sparkling Pink Barbie. Mexico City 'Barbie' premiere, Mexico (July 6 2023) Robbie wore a long-sleeve pink minidress at the Barbie Mexico premiere, but the accessories made the look complete with a silver belt and some huge dangly hearts and stars silver earrings for Earring Magic Barbie. Mexico photo call (July 7 2023) A bright patterned dress with fluorescent pink earring and crimped hair screams the 80s which means sense since the look is inspired by the Totally Hair 25th Anniversary Barbie. 'Barbie' world premiere in Los Angeles (July 9 2023) Ditching the pink (although not entirely with the delicately held handkerchief), Robbie stepped out in a black custom Schiaparelli haute couture dress to the LA premiere of Barbie. This look referenced Barbie’s Solo in the Spotlight dress from 1960, in which both the doll and Robbie wore black gloves, tulle fringe, and pink handkerchief. 'Barbie' European premiere, London (July 12 2023) Robbie stunned in a vintage Vivienne Westwood draped corset gown, which featured a white tulle stole, and was accessorised with matte ivory opera gloves and a layered pearl necklace. A look that was originally created for the Mattel doll back in the 1960s for Enchanted Evening Barbie. Elsewhere, here are 29 of the biggest Barbie brand collaborations ahead of the new movie, doctors warn against 'Barbie foot' challenge taking over TikTok and how old is Barbie supposed to be? Have your say in our news democracy. Click the upvote icon at the top of the page to help raise this article through the indy100 rankings.

I discovered the joys of hiking and trail running late in life, but once I started exploring scenic parks and trails just outside of New York as an adult, it was an easy sell. Not only are the views like therapy for the soul, but the endorphins I get from sweating it out and breathing in fresh, crisp air is the best kind of exercise I can think of. While I mostly run nowadays on a treadmill, it’s an understatement to say that it, well, doesn’t hit quite the same. And if Lululemon’s latest footwear launch is any indication, I’m not alone in that sentiment.

Helen Flanagan admits she’s “no superwoman”, and isn’t saying being a single parent is easy. But despite “running around like a blue-arsed fly” as she puts it, the former Coronation Street actress, who split from her footballer fiancé Scott Sinclair last summer, says her new single family life is working really well. “I co-parent with my ex-fiancé Scott – we’ve got three children together, and we were together for 13 years,” explains Flanagan, 32, who has just appeared on I’m A Celebrity… South Africa. “My friends help me with the children, because I do work nearly every day. I have a friend and we’re a girl gang together – I’m not superwoman! So that works nicely at home. “Scott’s living with his mum at the moment in Bristol, and my children are really close to their nana, so it works really well. My kids just have a really happy environment, with me and my friend at home, and then they have a really nice happy environment with their dad and their nana.” Flanagan, who lives in Manchester, says she has the children – Matilda, eight, Delilah, five, and two-year-old Charlie – “the majority of the time”, as their dad’s away playing football for Bristol Rovers a lot. “So it kind of can’t be helped, really,” she says. “But his mum is absolutely fantastic, we get on very, very well. She’s known me since I was 19, so I’m close with his mum, and she helps me a lot with the children.” The actress admits that although she misses her “babies” when they’re with their dad and nana, she makes the most of her child-free time. “I had my children not young, but young-ish – I had Matilda when I was 24 – and I just feel like I spent all my 20s being pregnant and breastfeeding at home,” Flanagan reflects. “So it’s kind of nice sometimes to have that time, because I know they’re in the best hands with Scott’s mum, and it’s lovely that I can spend some time with my friends and concentrate on my work and have some fun. So it’s nice, it works well. “Of course I miss them, they’re my babies, but I know they’re really, really happy with their nana and their dad, so I don’t have to worry. I do feel like the happier you are as a mum, the better it is for your child.” Most of Flanagan’s time these days is spent either working or looking after the kids – and deflecting her daughters’ pleas to get on social media. “I’m not ready for my five-year-old and eight-year-old to have social media yet – I don’t think it’s healthy for children to have social media too young,” she says. “Matilda’s desperate to go on TikTok and create her own content, and sometimes I feel a bit guilty because I’m on TikTok and Instagram and she sees that. So I said, ‘Why don’t you have mummy’s?’ and she said, ‘No, I want my own!’” As a compromise for the time being, the girls have been allowed a NickWatch connected smartwatch, which is free from social media but features games, music, safe connectivity with parents, and a GPS tracker. “A GPS tracker is such a comfort as a parent to have,” says Flanagan. “You can see where they are at all times, which is great. For me as a parent, I never keep my eyes off my children, they’re too precious. It’s just to have peace of mind.” New research by NickWatch found 41% of parents with a child under 10 years say their child has walked off on their own without them being aware. According to the survey, parents of children aged under 10 say they’ve ‘lost’ them five times on average. Fortunately, keeping a close eye on her kids means Flanagan has never been in that position, although she admits: “I’ve had a moment in a supermarket where I’ve kind of gone, ‘Where’s Matilda?’, and then I’ve seen her. But it’s common for people to lose their children, which is really scary – it’s the worst feeling in the world, and you need to have eyes in the back of your head.” But it was her daughter’s eyes that were on her, when Flanagan took part in I’m a Celebrity… South Africa recently, more than 10 years after she first took part in the show in the Australian jungle. “I loved the jungle, I really, really, did,” she declares. “It was just such anamazing experience. It was great to go back and redeem myself. I didn’t want to be pathetic and rubbish at the trials, and I had my little girl watching from home, so I couldn’t have not done it – she’d have been gutted, so that was my motivation.” Now she’s back, Flanagan, who last appeared as Rosie Webster on Coronation Street in 2018, says she’s currently doing a lot of work on social media and auditioning, and has “things in the pipeline that I can’t really share just now”. But she adds: “I’d absolutely love to go back to Coronation Street at some point, it’s just timing – I definitely want to do it at some point.” Helen Flanagan is helping to launch Nickwatch, a new connected smartwatch for children aged six to nine with built-in GPS tracking. Read More Strictly Come Dancing star Amy Dowden diagnosed with breast cancer aged 32 Joe Alwyn attends Celine dinner at Cannes Film Festival Madeleine McCann – latest news: Search of remote reservoir enters second day as police seen digging beside dam Charity boss speaks out over ‘traumatic’ encounter with royal aide Ukraine war’s heaviest fight rages in east - follow live

Max Verstappen will begin his quest to win the world championship from third for Saturday’s sprint race in Qatar as Oscar Piastri took a surprise pole position. Piastri saw off team-mate Lando Norris as McLaren secured a front-row lockout. Lewis Hamilton was knocked out of Q2 and qualified only 12th in his Mercedes for the 19-lap dash, which gets under way at 8:30pm local time (6:30pm BST). Verstappen will wrap up his third consecutive title if he finishes sixth or better, or if Red Bull team-mate Sergio Perez fails to finish inside the top three in the sprint at the Lusail International Circuit. Perez qualified only eighth on yet another scruffy outing for the struggling Mexican. A day after taking top spot for the start of Sunday’s 57-lap main event, Verstappen, who has dominated all year, saw his first lap in Q3 deleted for exceeding track limits at Turn 5. And the 26-year-old Dutchman was unable to do enough on his final run to usurp Piastri, finishing two tenths behind the rookie Australian. Norris was in the running for first place but he ran wide at the last corner and failed to improve on his earlier effort. George Russell finished fourth for Mercedes – four tenths behind Piastri – and ahead of Carlos Sainz and Charles Leclerc, who took fifth and sixth respectively for Ferrari. Sprint qualifying at a windswept Lusail – 18 miles north of Doha – was delayed amid fears over the safety of the tyres. The running had been due to start at 4pm local time (2pm BST), but was delayed by 20 minutes following revisions to the track limits. The drivers took part in an additional 10 minutes of practice to familiarise themselves with the changes made to the track at turns 12 and 13 prior to qualifying. Formula One’s governing body, the FIA, said “a separation in the sidewall between the topping compound and the carcass cords” were discovered on the Pirelli tyres following yesterday’s one-hour running. The federation believe the problem is likely to have been caused by a number of the high kerbs used at the circuit. An emergency summit was staged in the build-up to qualifying with the drivers assured they would not be put in harm’s way. Additional analysis will take place following today’s sprint race and further action – which will include three mandatory tyre stops – may be taken for Sunday’s grand prix. Lance Stroll shoved his British performance coach and stormed out of a television interview after he was eliminated from Q1 in Friday’s running. And the under-pressure Canadian fell at the first hurdle again on Saturday, one place better off in 16th. Stroll’s Aston Martin team-mate Fernando Alonso, who also saw his best effort in qualifying chalked off for exceeding track limits, lines up in ninth. Read More Angry Lance Stroll shoves personal trainer and storms out of interview Max Verstappen fastest in Qatar practice as he closes in on world championship Fernando Alonso lauds Max Verstappen as best F1 driver since Michael Schumacher Fernando Alonso lauds Max Verstappen as best F1 driver since Michael Schumacher Piastri takes first F1 pole for Qatar sprint as Verstappen starts third F1 Qatar Grand Prix LIVE: Sprint race updates and times at Lusail

Bud Light is trying to revive its slumping brand with a new marketing campaign aimed at -- appropriately -- overcoming adversity.

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